CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric RNASampler(20) RNASLOpt
MCC 0.686 > 0.560
Average MCC ± 95% Confidence Intervals 0.674 ± 0.323 > 0.598 ± 0.334
Sensitivity 0.603 > 0.543
Positive Predictive Value 0.787 > 0.589
Total TP 70 > 63
Total TN 9595 > 9577
Total FP 34 < 54
Total FP CONTRA 3 < 17
Total FP INCONS 16 < 27
Total FP COMP 15 > 10
Total FN 46 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and RNASLOpt).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 70
Total TN 9595
Total FP 34
Total FP CONTRA 3
Total FP INCONS 16
Total FP COMP 15
Total FN 46
Total Scores
MCC 0.686
Average MCC ± 95% Confidence Intervals 0.674 ± 0.323
Sensitivity 0.603
Positive Predictive Value 0.787
Nr of predictions 5

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.24 0.25 0.24 5 4495 30 3 13 14 15
4A1C_3 0.90 0.81 1.00 30 2733 0 0 0 0 7
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12
4ENB_A 0.68 0.47 1.00 7 465 0 0 0 0 8
4ENC_A 0.85 0.73 1.00 11 485 0 0 0 0 4

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 63
Total TN 9577
Total FP 54
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 10
Total FN 53
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.598 ± 0.334
Sensitivity 0.543
Positive Predictive Value 0.589
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.