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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of PPfold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & PPfold(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) PPfold(20)
MCC 0.683 > 0.676
Average MCC ± 95% Confidence Intervals 0.681 ± 0.337 > 0.651 ± 0.429
Sensitivity 0.593 < 0.604
Positive Predictive Value 0.794 > 0.764
Total TP 54 < 55
Total TN 7204 > 7200
Total FP 23 > 21
Total FP CONTRA 4 > 3
Total FP INCONS 10 < 14
Total FP COMP 9 > 4
Total FN 37 > 36
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and PPfold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and PPfold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 54
Total TN 7204
Total FP 23
Total FP CONTRA 4
Total FP INCONS 10
Total FP COMP 9
Total FN 37
Total Scores
MCC 0.683
Average MCC ± 95% Confidence Intervals 0.681 ± 0.337
Sensitivity 0.593
Positive Predictive Value 0.794
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of PPfold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 55
Total TN 7200
Total FP 21
Total FP CONTRA 3
Total FP INCONS 14
Total FP COMP 4
Total FN 36
Total Scores
MCC 0.676
Average MCC ± 95% Confidence Intervals 0.651 ± 0.429
Sensitivity 0.604
Positive Predictive Value 0.764
Nr of predictions 4

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.66 0.50 0.90 9 347 1 0 1 0 9
3RKF_A 0.86 0.79 0.95 19 846 1 0 1 0 5
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.