CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & RNAwolf [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) RNAwolf
MCC 0.559 > 0.521
Average MCC ± 95% Confidence Intervals 0.500 ± 0.651 < 0.525 ± 0.502
Sensitivity 0.484 < 0.538
Positive Predictive Value 0.657 > 0.516
Total TP 44 < 49
Total TN 7376 > 7348
Total FP 31 < 58
Total FP CONTRA 4 < 14
Total FP INCONS 19 < 32
Total FP COMP 8 < 12
Total FN 47 > 42
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and RNAwolf).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 7376
Total FP 31
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 8
Total FN 47
Total Scores
MCC 0.559
Average MCC ± 95% Confidence Intervals 0.500 ± 0.651
Sensitivity 0.484
Positive Predictive Value 0.657
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 49
Total TN 7348
Total FP 58
Total FP CONTRA 14
Total FP INCONS 32
Total FP COMP 12
Total FN 42
Total Scores
MCC 0.521
Average MCC ± 95% Confidence Intervals 0.525 ± 0.502
Sensitivity 0.538
Positive Predictive Value 0.516
Nr of predictions 4

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.50 0.56 9 512 7 0 7 0 9
3RKF_A 0.89 0.83 0.95 20 845 1 0 1 0 4
3SD1_A 0.58 0.59 0.59 17 1504 12 2 10 0 12
4A1C_2 0.12 0.15 0.10 3 4487 38 12 14 12 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.