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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric RNAalifold(20) RNASLOpt
MCC 0.656 > 0.560
Average MCC ± 95% Confidence Intervals 0.620 ± 0.344 > 0.598 ± 0.334
Sensitivity 0.578 > 0.543
Positive Predictive Value 0.753 > 0.589
Total TP 67 > 63
Total TN 9595 > 9577
Total FP 26 < 54
Total FP CONTRA 5 < 17
Total FP INCONS 17 < 27
Total FP COMP 4 < 10
Total FN 49 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(20) and RNASLOpt).

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Performance of RNAalifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 67
Total TN 9595
Total FP 26
Total FP CONTRA 5
Total FP INCONS 17
Total FP COMP 4
Total FN 49
Total Scores
MCC 0.656
Average MCC ± 95% Confidence Intervals 0.620 ± 0.344
Sensitivity 0.578
Positive Predictive Value 0.753
Nr of predictions 5

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.19 5 4490 23 5 16 2 15
4A1C_3 0.90 0.84 0.97 31 2731 1 0 1 0 6
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 63
Total TN 9577
Total FP 54
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 10
Total FN 53
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.598 ± 0.334
Sensitivity 0.543
Positive Predictive Value 0.589
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.