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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric TurboFold(20) RNASLOpt
MCC 0.655 > 0.560
Average MCC ± 95% Confidence Intervals 0.650 ± 0.308 > 0.598 ± 0.334
Sensitivity 0.612 > 0.543
Positive Predictive Value 0.710 > 0.589
Total TP 71 > 63
Total TN 9584 > 9577
Total FP 41 < 54
Total FP CONTRA 9 < 17
Total FP INCONS 20 < 27
Total FP COMP 12 > 10
Total FN 45 < 53
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and RNASLOpt).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 71
Total TN 9584
Total FP 41
Total FP CONTRA 9
Total FP INCONS 20
Total FP COMP 12
Total FN 45
Total Scores
MCC 0.655
Average MCC ± 95% Confidence Intervals 0.650 ± 0.308
Sensitivity 0.612
Positive Predictive Value 0.710
Nr of predictions 5

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 63
Total TN 9577
Total FP 54
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 10
Total FN 53
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.598 ± 0.334
Sensitivity 0.543
Positive Predictive Value 0.589
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.