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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) RNASampler(seed)
MCC 0.685 > 0.683
Average MCC ± 95% Confidence Intervals 0.697 ± 0.527 > 0.681 ± 0.337
Sensitivity 0.681 > 0.593
Positive Predictive Value 0.697 < 0.794
Total TP 62 > 54
Total TN 7183 < 7204
Total FP 37 > 23
Total FP CONTRA 8 > 4
Total FP INCONS 19 > 10
Total FP COMP 10 > 9
Total FN 29 < 37
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and RNASampler(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 62
Total TN 7183
Total FP 37
Total FP CONTRA 8
Total FP INCONS 19
Total FP COMP 10
Total FN 29
Total Scores
MCC 0.685
Average MCC ± 95% Confidence Intervals 0.697 ± 0.527
Sensitivity 0.681
Positive Predictive Value 0.697
Nr of predictions 4

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 54
Total TN 7204
Total FP 23
Total FP CONTRA 4
Total FP INCONS 10
Total FP COMP 9
Total FN 37
Total Scores
MCC 0.683
Average MCC ± 95% Confidence Intervals 0.681 ± 0.337
Sensitivity 0.593
Positive Predictive Value 0.794
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.