CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & RNAwolf [.zip] - may take several seconds...


Overview

Metric TurboFold(20) RNAwolf
MCC 0.712 > 0.453
Average MCC ± 95% Confidence Intervals 0.710 ± 0.177 > 0.465 ± 0.219
Sensitivity 0.670 > 0.447
Positive Predictive Value 0.764 > 0.475
Total TP 126 > 84
Total TN 13075 > 13063
Total FP 54 < 111
Total FP CONTRA 11 < 18
Total FP INCONS 28 < 75
Total FP COMP 15 < 18
Total FN 62 < 104
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(20) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and RNAwolf).

^top





Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 126
Total TN 13075
Total FP 54
Total FP CONTRA 11
Total FP INCONS 28
Total FP COMP 15
Total FN 62
Total Scores
MCC 0.712
Average MCC ± 95% Confidence Intervals 0.710 ± 0.177
Sensitivity 0.670
Positive Predictive Value 0.764
Nr of predictions 8

^top



2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.81 0.79 0.83 15 1139 6 0 3 3 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

^top



Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 84
Total TN 13063
Total FP 111
Total FP CONTRA 18
Total FP INCONS 75
Total FP COMP 18
Total FN 104
Total Scores
MCC 0.453
Average MCC ± 95% Confidence Intervals 0.465 ± 0.219
Sensitivity 0.447
Positive Predictive Value 0.475
Nr of predictions 8

^top



2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.77 0.79 0.75 15 1137 8 0 5 3 4
3RKF_A 0.89 0.83 0.95 20 845 1 0 1 0 4
3SD1_A 0.58 0.59 0.59 17 1504 12 2 10 0 12
4A1C_3 0.32 0.30 0.35 11 2732 21 1 19 1 26
4A1C_2 0.12 0.15 0.10 3 4487 38 12 14 12 17
4AOB_A 0.26 0.24 0.30 7 1414 17 2 14 1 22
4ENB_A 0.45 0.40 0.55 6 461 5 1 4 0 9
4ENC_A 0.34 0.33 0.38 5 483 9 0 8 1 10

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.