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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) TurboFold(seed)
MCC 0.725 > 0.712
Average MCC ± 95% Confidence Intervals 0.726 ± 0.188 > 0.723 ± 0.195
Sensitivity 0.684 = 0.684
Positive Predictive Value 0.776 > 0.749
Total TP 128 = 128
Total TN 12275 > 12269
Total FP 50 < 59
Total FP CONTRA 11 < 14
Total FP INCONS 26 < 29
Total FP COMP 13 < 16
Total FN 59 = 59
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and TurboFold(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 128
Total TN 12275
Total FP 50
Total FP CONTRA 11
Total FP INCONS 26
Total FP COMP 13
Total FN 59
Total Scores
MCC 0.725
Average MCC ± 95% Confidence Intervals 0.726 ± 0.188
Sensitivity 0.684
Positive Predictive Value 0.776
Nr of predictions 8

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 128
Total TN 12269
Total FP 59
Total FP CONTRA 14
Total FP INCONS 29
Total FP COMP 16
Total FN 59
Total Scores
MCC 0.712
Average MCC ± 95% Confidence Intervals 0.723 ± 0.195
Sensitivity 0.684
Positive Predictive Value 0.749
Nr of predictions 8

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.