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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of UNAFold - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & UNAFold [.zip] - may take several seconds...


Overview

Metric TurboFold(20) UNAFold
MCC 0.733 > 0.706
Average MCC ± 95% Confidence Intervals 0.735 ± 0.163 > 0.709 ± 0.207
Sensitivity 0.694 < 0.704
Positive Predictive Value 0.781 > 0.718
Total TP 143 < 145
Total TN 13414 > 13395
Total FP 56 < 82
Total FP CONTRA 11 < 19
Total FP INCONS 29 < 38
Total FP COMP 16 < 25
Total FN 63 > 61
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and UNAFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and UNAFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and UNAFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and UNAFold).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 143
Total TN 13414
Total FP 56
Total FP CONTRA 11
Total FP INCONS 29
Total FP COMP 16
Total FN 63
Total Scores
MCC 0.733
Average MCC ± 95% Confidence Intervals 0.735 ± 0.163
Sensitivity 0.694
Positive Predictive Value 0.781
Nr of predictions 9

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3AMU_B 0.81 0.79 0.83 15 1139 6 0 3 3 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of UNAFold - scored lower in this pairwise comparison

1. Total counts & total scores for UNAFold

Total Base Pair Counts
Total TP 145
Total TN 13395
Total FP 82
Total FP CONTRA 19
Total FP INCONS 38
Total FP COMP 25
Total FN 61
Total Scores
MCC 0.706
Average MCC ± 95% Confidence Intervals 0.709 ± 0.207
Sensitivity 0.704
Positive Predictive Value 0.718
Nr of predictions 9

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2. Individual counts for UNAFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
3AMU_B 0.81 0.79 0.83 15 1139 6 0 3 3 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.77 0.76 0.79 22 1505 6 4 2 0 7
4A1C_2 0.19 0.25 0.15 5 4483 42 11 17 14 15
4A1C_3 0.88 0.86 0.89 32 2727 7 0 4 3 5
4AOB_A 0.60 0.59 0.63 17 1410 11 4 6 1 12
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.37 0.33 0.45 5 485 7 0 6 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.