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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) RNASLOpt
MCC 0.552 > 0.551
Average MCC ± 95% Confidence Intervals 0.532 ± 0.378 < 0.579 ± 0.257
Sensitivity 0.530 > 0.522
Positive Predictive Value 0.587 < 0.593
Total TP 71 > 70
Total TN 10091 < 10094
Total FP 65 > 58
Total FP CONTRA 15 < 17
Total FP INCONS 35 > 31
Total FP COMP 15 > 10
Total FN 63 < 64
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and RNASLOpt).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 71
Total TN 10091
Total FP 65
Total FP CONTRA 15
Total FP INCONS 35
Total FP COMP 15
Total FN 63
Total Scores
MCC 0.552
Average MCC ± 95% Confidence Intervals 0.532 ± 0.378
Sensitivity 0.530
Positive Predictive Value 0.587
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 70
Total TN 10094
Total FP 58
Total FP CONTRA 17
Total FP INCONS 31
Total FP COMP 10
Total FN 64
Total Scores
MCC 0.551
Average MCC ± 95% Confidence Intervals 0.579 ± 0.257
Sensitivity 0.522
Positive Predictive Value 0.593
Nr of predictions 6

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.