CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Alterna - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Alterna & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric Alterna Murlet(seed)
MCC 0.758 > 0.594
Average MCC ± 95% Confidence Intervals 0.782 ± 0.104 > 0.590 ± 0.103
Sensitivity 0.676 > 0.425
Positive Predictive Value 0.854 > 0.839
Total TP 299 > 188
Total TN 35995 < 36121
Total FP 68 > 39
Total FP CONTRA 4 = 4
Total FP INCONS 47 > 32
Total FP COMP 17 > 3
Total FN 143 < 254
P-value 2.66715895098e-08

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Performance plots


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Performance of Alterna - scored higher in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 299
Total TN 35995
Total FP 68
Total FP CONTRA 4
Total FP INCONS 47
Total FP COMP 17
Total FN 143
Total Scores
MCC 0.758
Average MCC ± 95% Confidence Intervals 0.782 ± 0.104
Sensitivity 0.676
Positive Predictive Value 0.854
Nr of predictions 17

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2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.92 0.89 0.94 17 1110 2 0 1 1 2
2KUR_A 0.90 0.86 0.95 18 1109 1 0 1 0 3
2KUU_A 0.87 0.81 0.94 17 1110 2 0 1 1 4
2KUV_A 0.88 0.82 0.95 18 1109 1 0 1 0 4
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.46 0.40 0.53 8 1525 7 0 7 0 12
2XKV_B 0.45 0.45 0.45 9 4540 25 0 11 14 11
3A3A_A 0.84 0.70 1.00 26 3629 0 0 0 0 11
3GX2_A 0.47 0.40 0.57 16 4343 13 1 11 1 24
3IVN_B 0.74 0.61 0.90 19 2325 2 1 1 0 12
3LA5_A 0.78 0.62 1.00 21 2464 0 0 0 0 13
3RKF_A 0.69 0.56 0.86 19 2189 3 1 2 0 15
3SD1_A 0.46 0.38 0.57 16 3888 12 1 11 0 26

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 188
Total TN 36121
Total FP 39
Total FP CONTRA 4
Total FP INCONS 32
Total FP COMP 3
Total FN 254
Total Scores
MCC 0.594
Average MCC ± 95% Confidence Intervals 0.590 ± 0.103
Sensitivity 0.425
Positive Predictive Value 0.839
Nr of predictions 17

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.52 0.27 1.00 3 403 0 0 0 0 8
2KE6_A 0.66 0.53 0.83 10 1116 2 0 2 0 9
2KUR_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUU_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUV_A 0.85 0.73 1.00 16 1112 0 0 0 0 6
2KUW_A 0.84 0.76 0.94 16 1111 1 0 1 0 5
2L1F_B 0.80 0.72 0.90 18 2125 2 0 2 0 7
2L1F_A 0.82 0.75 0.90 18 2060 2 0 2 0 6
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
3A3A_A 0.57 0.32 1.00 12 3643 0 0 0 0 25
3GX2_A 0.59 0.35 1.00 14 4357 1 0 0 1 26
3IVN_B 0.53 0.39 0.75 12 2330 4 2 2 0 19
3LA5_A 0.58 0.41 0.82 14 2468 3 1 2 0 20
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.