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Table of contents:
- Overview
- Performance Plots
- Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison
- Performance of RDfolder - scored lower in this pairwise comparison
- Compile and download dataset for CentroidHomfold‑LAST & RDfolder [.zip] - may take several seconds...
Overview
| Metric | CentroidHomfold‑LAST | RDfolder | |
|---|---|---|---|
| MCC | 0.706 | > | 0.538 |
| Average MCC ± 95% Confidence Intervals | 0.705 ± 0.107 | > | 0.592 ± 0.124 |
| Sensitivity | 0.542 | > | 0.425 |
| Positive Predictive Value | 0.927 | > | 0.693 |
| Total TP | 279 | > | 219 |
| Total TN | 36084 | > | 36069 |
| Total FP | 34 | < | 107 |
| Total FP CONTRA | 0 | < | 12 |
| Total FP INCONS | 22 | < | 85 |
| Total FP COMP | 12 | > | 10 |
| Total FN | 236 | < | 296 |
| P-value | 3.56938820447e-08 | ||
Performance plots
Performance of CentroidHomfold‑LAST - scored higher in this pairwise comparison
1. Total counts & total scores for CentroidHomfold‑LAST
| Total Base Pair Counts | |
|---|---|
| Total TP | 279 |
| Total TN | 36084 |
| Total FP | 34 |
| Total FP CONTRA | 0 |
| Total FP INCONS | 22 |
| Total FP COMP | 12 |
| Total FN | 236 |
| Total Scores | |
|---|---|
| MCC | 0.706 |
| Average MCC ± 95% Confidence Intervals | 0.705 ± 0.107 |
| Sensitivity | 0.542 |
| Positive Predictive Value | 0.927 |
| Nr of predictions | 32 |
2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2L94_A | 0.92 | 0.90 | 0.95 | 18 | 971 | 1 | 0 | 1 | 0 | 2 | |
| 2LA5_A | - | 0.46 | 0.26 | 0.83 | 5 | 624 | 1 | 0 | 1 | 0 | 14 |
| 2LBS_A | - | 1.00 | 1.00 | 1.00 | 14 | 482 | 0 | 0 | 0 | 0 | 0 |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1529 | 11 | 0 | 11 | 0 | 20 | |
| 2LDL_A | - | 0.90 | 0.82 | 1.00 | 9 | 342 | 1 | 0 | 0 | 1 | 2 |
| 2LDT_A | - | 0.72 | 0.53 | 1.00 | 8 | 457 | 0 | 0 | 0 | 0 | 7 |
| 2LK3_A | - | 0.95 | 0.90 | 1.00 | 9 | 267 | 0 | 0 | 0 | 0 | 1 |
| 2RRC_A | - | 0.70 | 0.50 | 1.00 | 5 | 226 | 0 | 0 | 0 | 0 | 5 |
| 2Y8W_B | - | 1.00 | 1.00 | 1.00 | 6 | 184 | 1 | 0 | 0 | 1 | 0 |
| 2Y9C_V | - | 0.20 | 0.04 | 1.00 | 1 | 2277 | 0 | 0 | 0 | 0 | 23 |
| 2YIE_X | - | 0.76 | 0.58 | 1.00 | 7 | 1371 | 0 | 0 | 0 | 0 | 5 |
| 2YIE_Z | - | 0.82 | 0.67 | 1.00 | 8 | 1532 | 0 | 0 | 0 | 0 | 4 |
| 3AMU_B | 0.82 | 0.70 | 0.95 | 19 | 2983 | 3 | 0 | 1 | 2 | 8 | |
| 3J0L_a | - | -0.01 | 0.00 | 0.00 | 0 | 1125 | 3 | 0 | 3 | 0 | 16 |
| 3J0L_8 | - | 0.93 | 0.88 | 1.00 | 7 | 183 | 0 | 0 | 0 | 0 | 1 |
| 3J0L_1 | - | 0.65 | 0.47 | 0.90 | 9 | 1215 | 2 | 0 | 1 | 1 | 10 |
| 3J0L_7 | - | 0.60 | 0.41 | 0.88 | 7 | 1217 | 1 | 0 | 1 | 0 | 10 |
| 3J0L_g | - | 0.00 | 0.00 | 0.00 | 0 | 465 | 0 | 0 | 0 | 0 | 4 |
| 3J16_L | 0.75 | 0.57 | 1.00 | 17 | 2758 | 0 | 0 | 0 | 0 | 13 | |
| 3NMU_E | - | 0.41 | 0.17 | 1.00 | 1 | 560 | 3 | 0 | 0 | 3 | 5 |
| 3R9X_C | - | 0.84 | 0.80 | 0.89 | 8 | 586 | 2 | 0 | 1 | 1 | 2 |
| 3RKF_A | 0.72 | 0.53 | 1.00 | 18 | 2193 | 0 | 0 | 0 | 0 | 16 | |
| 3SD1_A | 0.64 | 0.45 | 0.90 | 19 | 3895 | 2 | 0 | 2 | 0 | 23 | |
| 3SIU_F | - | 0.73 | 0.55 | 1.00 | 6 | 372 | 0 | 0 | 0 | 0 | 5 |
| 3SN2_B | 0.91 | 0.83 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 2 | |
| 3TRZ_Z | - | 0.91 | 0.83 | 1.00 | 5 | 205 | 1 | 0 | 0 | 1 | 1 |
| 3TS0_U | - | 1.00 | 1.00 | 1.00 | 6 | 247 | 1 | 0 | 0 | 1 | 0 |
| 3TS2_V | - | 1.00 | 1.00 | 1.00 | 5 | 271 | 0 | 0 | 0 | 0 | 0 |
| 4A4U_A | - | 1.00 | 1.00 | 1.00 | 9 | 222 | 0 | 0 | 0 | 0 | 0 |
| 4AOB_A | 0.71 | 0.50 | 1.00 | 21 | 4350 | 1 | 0 | 0 | 1 | 21 | |
| 4ENB_A | 0.76 | 0.58 | 1.00 | 11 | 1264 | 0 | 0 | 0 | 0 | 8 | |
| 4ENC_A | 0.76 | 0.58 | 1.00 | 11 | 1315 | 0 | 0 | 0 | 0 | 8 |
Performance of RDfolder - scored lower in this pairwise comparison
1. Total counts & total scores for RDfolder
| Total Base Pair Counts | |
|---|---|
| Total TP | 219 |
| Total TN | 36069 |
| Total FP | 107 |
| Total FP CONTRA | 12 |
| Total FP INCONS | 85 |
| Total FP COMP | 10 |
| Total FN | 296 |
| Total Scores | |
|---|---|
| MCC | 0.538 |
| Average MCC ± 95% Confidence Intervals | 0.592 ± 0.124 |
| Sensitivity | 0.425 |
| Positive Predictive Value | 0.693 |
| Nr of predictions | 32 |
2. Individual counts for RDfolder [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2LA5_A | - | 0.46 | 0.26 | 0.83 | 5 | 624 | 1 | 0 | 1 | 0 | 14 |
| 2LBS_A | - | 1.00 | 1.00 | 1.00 | 14 | 482 | 0 | 0 | 0 | 0 | 0 |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1526 | 14 | 2 | 12 | 0 | 20 | |
| 2LDL_A | - | 0.90 | 0.82 | 1.00 | 9 | 342 | 0 | 0 | 0 | 0 | 2 |
| 2LDT_A | - | 0.68 | 0.47 | 1.00 | 7 | 458 | 0 | 0 | 0 | 0 | 8 |
| 2LK3_A | - | 0.95 | 0.90 | 1.00 | 9 | 267 | 0 | 0 | 0 | 0 | 1 |
| 2RRC_A | - | 0.70 | 0.50 | 1.00 | 5 | 226 | 0 | 0 | 0 | 0 | 5 |
| 2Y8W_B | - | 1.00 | 1.00 | 1.00 | 6 | 184 | 1 | 0 | 0 | 1 | 0 |
| 2Y9C_V | - | 0.57 | 0.50 | 0.67 | 12 | 2260 | 7 | 1 | 5 | 1 | 12 |
| 2YIE_X | - | 0.38 | 0.33 | 0.44 | 4 | 1369 | 5 | 1 | 4 | 0 | 8 |
| 2YIE_Z | - | 0.43 | 0.42 | 0.45 | 5 | 1529 | 6 | 3 | 3 | 0 | 7 |
| 3AMU_B | 0.18 | 0.15 | 0.22 | 4 | 2985 | 16 | 2 | 12 | 2 | 23 | |
| 3J0L_a | - | -0.01 | 0.00 | 0.00 | 0 | 1124 | 4 | 1 | 3 | 0 | 16 |
| 3J0L_8 | - | 0.86 | 0.75 | 1.00 | 6 | 184 | 0 | 0 | 0 | 0 | 2 |
| 3J0L_1 | - | 0.65 | 0.47 | 0.90 | 9 | 1215 | 2 | 0 | 1 | 1 | 10 |
| 3J0L_7 | - | -0.01 | 0.00 | 0.00 | 0 | 1220 | 5 | 0 | 5 | 0 | 17 |
| 3J0L_g | - | -0.01 | 0.00 | 0.00 | 0 | 462 | 3 | 1 | 2 | 0 | 4 |
| 3J16_L | 0.22 | 0.17 | 0.31 | 5 | 2759 | 11 | 0 | 11 | 0 | 25 | |
| 3NMU_E | - | 0.41 | 0.17 | 1.00 | 1 | 560 | 3 | 0 | 0 | 3 | 5 |
| 3R9X_C | - | 0.84 | 0.80 | 0.89 | 8 | 586 | 2 | 0 | 1 | 1 | 2 |
| 3RKF_A | 0.76 | 0.59 | 1.00 | 20 | 2191 | 0 | 0 | 0 | 0 | 14 | |
| 3SD1_A | 0.30 | 0.17 | 0.54 | 7 | 3903 | 6 | 0 | 6 | 0 | 35 | |
| 3SIU_F | - | 0.73 | 0.55 | 1.00 | 6 | 372 | 0 | 0 | 0 | 0 | 5 |
| 3SN2_B | 0.96 | 0.92 | 1.00 | 11 | 395 | 0 | 0 | 0 | 0 | 1 | |
| 3TRZ_Z | - | 0.91 | 0.83 | 1.00 | 5 | 205 | 0 | 0 | 0 | 0 | 1 |
| 3TS0_U | - | 0.91 | 0.83 | 1.00 | 5 | 248 | 0 | 0 | 0 | 0 | 1 |
| 3TS2_V | - | 1.00 | 1.00 | 1.00 | 5 | 271 | 0 | 0 | 0 | 0 | 0 |
| 4A4U_A | - | 1.00 | 1.00 | 1.00 | 9 | 222 | 0 | 0 | 0 | 0 | 0 |
| 4AOB_A | 0.35 | 0.26 | 0.48 | 11 | 4348 | 13 | 1 | 11 | 1 | 31 | |
| 4ENB_A | 0.43 | 0.32 | 0.60 | 6 | 1265 | 4 | 0 | 4 | 0 | 13 | |
| 4ENC_A | 0.43 | 0.32 | 0.60 | 6 | 1316 | 4 | 0 | 4 | 0 | 13 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.