CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Contrafold - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Contrafold [.zip] - may take several seconds...


Overview

Metric ContextFold Contrafold
MCC 0.705 > 0.649
Average MCC ± 95% Confidence Intervals 0.739 ± 0.100 > 0.707 ± 0.112
Sensitivity 0.594 > 0.568
Positive Predictive Value 0.843 > 0.749
Total TP 360 > 344
Total TN 64163 > 64131
Total FP 90 < 139
Total FP CONTRA 6 < 16
Total FP INCONS 61 < 99
Total FP COMP 23 < 24
Total FN 246 < 262
P-value 3.56938820447e-08

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Performance plots


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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 360
Total TN 64163
Total FP 90
Total FP CONTRA 6
Total FP INCONS 61
Total FP COMP 23
Total FN 246
Total Scores
MCC 0.705
Average MCC ± 95% Confidence Intervals 0.739 ± 0.100
Sensitivity 0.594
Positive Predictive Value 0.843
Nr of predictions 30

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.55 0.50 0.63 10 1524 6 0 6 0 10
2LDL_A - 0.90 0.82 1.00 9 342 0 0 0 0 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 0.93 0.88 1.00 7 344 2 0 0 2 1
2LK3_A - 0.89 0.80 1.00 8 268 0 0 0 0 2
2LKR_A - 0.65 0.56 0.76 22 6076 9 0 7 2 17
2LQZ_A - 0.80 0.73 0.89 8 342 1 1 0 0 3
2LWK_A - 0.88 0.85 0.92 11 484 1 0 1 0 2
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_a - 0.71 0.56 0.90 9 1118 1 0 1 0 7
3J0L_1 - 0.70 0.58 0.85 11 1212 3 0 2 1 8
3J0L_h - 0.82 0.67 1.00 29 6076 2 0 0 2 14
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 462 3 1 2 0 4
3J0L_2 - 0.64 0.61 0.69 20 6187 11 2 7 2 13
3J16_L 0.75 0.57 1.00 17 2758 0 0 0 0 13
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 0 0 0 0 1
3TS0_U - 1.00 1.00 1.00 6 247 0 0 0 0 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.75 0.57 1.00 21 3139 0 0 0 0 16
3UZL_B 0.72 0.54 0.95 20 3549 1 0 1 0 17
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.78 0.63 0.97 34 7105 1 0 1 0 20
4A1C_2 0.20 0.15 0.28 5 11763 26 0 13 13 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.52 0.40 0.68 17 4346 9 1 7 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Contrafold - scored lower in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 344
Total TN 64131
Total FP 139
Total FP CONTRA 16
Total FP INCONS 99
Total FP COMP 24
Total FN 262
Total Scores
MCC 0.649
Average MCC ± 95% Confidence Intervals 0.707 ± 0.112
Sensitivity 0.568
Positive Predictive Value 0.749
Nr of predictions 30

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.45 0.35 0.58 7 1528 5 2 3 0 13
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 1.00 1.00 1.00 8 343 2 0 0 2 0
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.84 0.79 0.89 31 6070 6 0 4 2 8
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2LWK_A - 0.88 0.85 0.92 11 484 1 0 1 0 2
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_a - 0.50 0.44 0.58 7 1116 5 2 3 0 9
3J0L_1 - 0.73 0.58 0.92 11 1213 2 0 1 1 8
3J0L_h - 0.75 0.65 0.88 28 6073 6 0 4 2 15
3J0L_7 - -0.01 0.00 0.00 0 1218 7 0 7 0 17
3J0L_g - 0.00 0.00 0.00 0 464 1 1 0 0 4
3J0L_2 - 0.25 0.24 0.28 8 6187 26 0 21 5 25
3J16_L 0.46 0.40 0.55 12 2753 10 1 9 0 18
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 1 0 0 1 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.59 0.46 0.77 17 3138 5 0 5 0 20
3UZL_B 0.70 0.54 0.91 20 3548 2 0 2 0 17
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.66 0.57 0.78 31 7100 9 1 8 0 23
4A1C_2 0.16 0.15 0.17 5 11751 33 5 20 8 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.44 0.36 0.56 15 4344 13 1 11 1 27
4ENB_A 0.73 0.58 0.92 11 1263 1 1 0 0 8
4ENC_A 0.73 0.58 0.92 11 1314 1 1 0 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.