CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of RNAsubopt - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & RNAsubopt [.zip] - may take several seconds...


Overview

Metric ContextFold RNAsubopt
MCC 0.705 > 0.584
Average MCC ± 95% Confidence Intervals 0.739 ± 0.100 > 0.658 ± 0.128
Sensitivity 0.594 > 0.525
Positive Predictive Value 0.843 > 0.658
Total TP 360 > 318
Total TN 64163 > 64107
Total FP 90 < 191
Total FP CONTRA 6 < 15
Total FP INCONS 61 < 150
Total FP COMP 23 < 26
Total FN 246 < 288
P-value 3.56938820447e-08

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Performance plots


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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 360
Total TN 64163
Total FP 90
Total FP CONTRA 6
Total FP INCONS 61
Total FP COMP 23
Total FN 246
Total Scores
MCC 0.705
Average MCC ± 95% Confidence Intervals 0.739 ± 0.100
Sensitivity 0.594
Positive Predictive Value 0.843
Nr of predictions 30

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.55 0.50 0.63 10 1524 6 0 6 0 10
2LDL_A - 0.90 0.82 1.00 9 342 0 0 0 0 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 0.93 0.88 1.00 7 344 2 0 0 2 1
2LK3_A - 0.89 0.80 1.00 8 268 0 0 0 0 2
2LKR_A - 0.65 0.56 0.76 22 6076 9 0 7 2 17
2LQZ_A - 0.80 0.73 0.89 8 342 1 1 0 0 3
2LWK_A - 0.88 0.85 0.92 11 484 1 0 1 0 2
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_a - 0.71 0.56 0.90 9 1118 1 0 1 0 7
3J0L_1 - 0.70 0.58 0.85 11 1212 3 0 2 1 8
3J0L_h - 0.82 0.67 1.00 29 6076 2 0 0 2 14
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 462 3 1 2 0 4
3J0L_2 - 0.64 0.61 0.69 20 6187 11 2 7 2 13
3J16_L 0.75 0.57 1.00 17 2758 0 0 0 0 13
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 0 0 0 0 1
3TS0_U - 1.00 1.00 1.00 6 247 0 0 0 0 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.75 0.57 1.00 21 3139 0 0 0 0 16
3UZL_B 0.72 0.54 0.95 20 3549 1 0 1 0 17
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.78 0.63 0.97 34 7105 1 0 1 0 20
4A1C_2 0.20 0.15 0.28 5 11763 26 0 13 13 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.52 0.40 0.68 17 4346 9 1 7 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of RNAsubopt - scored lower in this pairwise comparison

1. Total counts & total scores for RNAsubopt

Total Base Pair Counts
Total TP 318
Total TN 64107
Total FP 191
Total FP CONTRA 15
Total FP INCONS 150
Total FP COMP 26
Total FN 288
Total Scores
MCC 0.584
Average MCC ± 95% Confidence Intervals 0.658 ± 0.128
Sensitivity 0.525
Positive Predictive Value 0.658
Nr of predictions 30

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2. Individual counts for RNAsubopt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 1.00 1.00 1.00 8 343 2 0 0 2 0
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.81 0.77 0.86 30 6070 9 0 5 4 9
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2LWK_A - 0.83 0.77 0.91 10 485 1 0 1 0 3
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_a - 0.35 0.31 0.42 5 1116 7 1 6 0 11
3J0L_1 - 0.76 0.63 0.92 12 1212 2 0 1 1 7
3J0L_h - 0.75 0.60 0.93 26 6077 4 0 2 2 17
3J0L_7 - -0.01 0.00 0.00 0 1213 12 0 12 0 17
3J0L_g - -0.01 0.00 0.00 0 460 5 1 4 0 4
3J0L_2 - 0.25 0.24 0.28 8 6187 25 0 21 4 25
3J16_L 0.41 0.37 0.48 11 2752 12 1 11 0 19
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 1 0 0 1 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
3UZL_B 0.48 0.38 0.61 14 3547 9 0 9 0 23
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.70 0.59 0.82 32 7101 7 1 6 0 22
4A1C_2 0.14 0.15 0.13 5 11742 43 5 29 9 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.52 0.43 0.64 18 4343 11 2 8 1 24
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.32 0.26 0.42 5 1314 7 0 7 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.