CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Contrafold - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Contrafold & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric Contrafold Murlet(seed)
MCC 0.654 > 0.539
Average MCC ± 95% Confidence Intervals 0.697 ± 0.110 > 0.545 ± 0.074
Sensitivity 0.582 > 0.337
Positive Predictive Value 0.740 < 0.868
Total TP 456 > 264
Total TN 104183 < 104495
Total FP 199 > 46
Total FP CONTRA 24 > 5
Total FP INCONS 136 > 35
Total FP COMP 39 > 6
Total FN 327 < 519
P-value 5.1503931209e-08

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Performance plots


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Performance of Contrafold - scored higher in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 456
Total TN 104183
Total FP 199
Total FP CONTRA 24
Total FP INCONS 136
Total FP COMP 39
Total FN 327
Total Scores
MCC 0.654
Average MCC ± 95% Confidence Intervals 0.697 ± 0.110
Sensitivity 0.582
Positive Predictive Value 0.740
Nr of predictions 26

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.97 0.95 1.00 18 1110 1 0 0 1 1
2KUR_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2KUU_A 0.92 0.86 1.00 18 1110 1 0 0 1 3
2KUV_A 0.93 0.86 1.00 19 1109 0 0 0 0 3
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
2LC8_A 0.45 0.35 0.58 7 1528 5 2 3 0 13
2XKV_B 0.51 0.50 0.53 10 4541 25 0 9 16 10
2XXA_G 0.13 0.12 0.15 5 5117 29 1 28 0 37
3A3A_A 0.87 0.76 1.00 28 3627 0 0 0 0 9
3GX2_A 0.77 0.63 0.96 25 4345 2 0 1 1 15
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.20 0.21 0.20 7 12211 35 6 22 7 26
3LA5_A 0.78 0.62 1.00 21 2464 0 0 0 0 13
3NPB_A 0.76 0.70 0.84 32 6983 8 1 5 2 14
3O58_3 0.28 0.26 0.31 9 12374 20 3 17 0 26
3PDR_A 0.69 0.60 0.80 43 12826 13 0 11 2 29
3RKF_A 0.73 0.59 0.91 20 2189 2 1 1 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 2 7 0 22
4A1C_2 0.16 0.15 0.17 5 11751 33 5 20 8 28
4AOB_A 0.44 0.36 0.56 15 4344 13 1 11 1 27
4ENB_A 0.73 0.58 0.92 11 1263 1 1 0 0 8
4ENC_A 0.73 0.58 0.92 11 1314 1 1 0 0 8

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 264
Total TN 104495
Total FP 46
Total FP CONTRA 5
Total FP INCONS 35
Total FP COMP 6
Total FN 519
Total Scores
MCC 0.539
Average MCC ± 95% Confidence Intervals 0.545 ± 0.074
Sensitivity 0.337
Positive Predictive Value 0.868
Nr of predictions 26

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.52 0.27 1.00 3 403 0 0 0 0 8
2KE6_A 0.66 0.53 0.83 10 1116 2 0 2 0 9
2KUR_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUU_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUV_A 0.85 0.73 1.00 16 1112 0 0 0 0 6
2KUW_A 0.84 0.76 0.94 16 1111 1 0 1 0 5
2L1F_A 0.82 0.75 0.90 18 2060 2 0 2 0 6
2L1F_B 0.80 0.72 0.90 18 2125 2 0 2 0 7
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
2XXA_G 0.38 0.14 1.00 6 5145 0 0 0 0 36
3A3A_A 0.57 0.32 1.00 12 3643 0 0 0 0 25
3GX2_A 0.59 0.35 1.00 14 4357 1 0 0 1 26
3IVN_B 0.53 0.39 0.75 12 2330 4 2 2 0 19
3JYX_4 0.23 0.09 0.60 3 12241 4 0 2 2 30
3LA5_A 0.58 0.41 0.82 14 2468 3 1 2 0 20
3NPB_A 0.49 0.28 0.87 13 7006 2 1 1 0 33
3O58_3 0.45 0.20 1.00 7 12396 0 0 0 0 28
3PDR_A 0.44 0.19 1.00 14 12866 0 0 0 0 58
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.