CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Contrafold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Contrafold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric Contrafold RNASampler(seed)
MCC 0.689 > 0.673
Average MCC ± 95% Confidence Intervals 0.741 ± 0.151 > 0.690 ± 0.136
Sensitivity 0.630 > 0.535
Positive Predictive Value 0.759 < 0.851
Total TP 283 > 240
Total TN 60986 < 61077
Total FP 107 > 59
Total FP CONTRA 19 > 4
Total FP INCONS 71 > 38
Total FP COMP 17 = 17
Total FN 166 < 209
P-value 4.44851456278e-08

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Performance plots


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Performance of Contrafold - scored higher in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 283
Total TN 60986
Total FP 107
Total FP CONTRA 19
Total FP INCONS 71
Total FP COMP 17
Total FN 166
Total Scores
MCC 0.689
Average MCC ± 95% Confidence Intervals 0.741 ± 0.151
Sensitivity 0.630
Positive Predictive Value 0.759
Nr of predictions 17

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.97 0.95 1.00 18 1110 1 0 0 1 1
2KUR_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2KUU_A 0.92 0.86 1.00 18 1110 1 0 0 1 3
2KUV_A 0.93 0.86 1.00 19 1109 0 0 0 0 3
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
2LC8_A 0.45 0.35 0.58 7 1528 5 2 3 0 13
3A3A_A 0.87 0.76 1.00 28 3627 0 0 0 0 9
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.20 0.21 0.20 7 12211 35 6 22 7 26
3O58_3 0.28 0.26 0.31 9 12374 20 3 17 0 26
3RKF_A 0.73 0.59 0.91 20 2189 2 1 1 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 2 7 0 22
4A1C_2 0.16 0.15 0.17 5 11751 33 5 20 8 28

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 240
Total TN 61077
Total FP 59
Total FP CONTRA 4
Total FP INCONS 38
Total FP COMP 17
Total FN 209
Total Scores
MCC 0.673
Average MCC ± 95% Confidence Intervals 0.690 ± 0.136
Sensitivity 0.535
Positive Predictive Value 0.851
Nr of predictions 17

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.92 0.84 1.00 16 1112 1 0 0 1 3
2KUR_A 0.90 0.81 1.00 17 1111 0 0 0 0 4
2KUU_A 0.87 0.76 1.00 16 1112 1 0 0 1 5
2KUV_A 0.88 0.77 1.00 17 1111 0 0 0 0 5
2KUW_A 0.90 0.81 1.00 17 1111 0 0 0 0 4
2L1F_A 0.81 0.67 1.00 16 2064 0 0 0 0 8
2L1F_B 0.82 0.68 1.00 17 2128 0 0 0 0 8
2L94_A 0.71 0.55 0.92 11 978 1 0 1 0 9
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3A3A_A 0.70 0.49 1.00 18 3637 0 0 0 0 19
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.39 0.30 0.50 10 12226 13 2 8 3 23
3O58_3 0.45 0.34 0.60 12 12383 12 2 6 4 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.