CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold Carnac(seed)
MCC 0.625 > 0.212
Average MCC ± 95% Confidence Intervals 0.661 ± 0.144 > 0.095 ± 0.149
Sensitivity 0.538 > 0.045
Positive Predictive Value 0.731 < 1.000
Total TP 272 > 23
Total TN 68639 < 68988
Total FP 122 > 0
Total FP CONTRA 15 > 0
Total FP INCONS 85 > 0
Total FP COMP 22 > 0
Total FN 234 < 483
P-value 2.76499031155e-08

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Performance plots


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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 272
Total TN 68639
Total FP 122
Total FP CONTRA 15
Total FP INCONS 85
Total FP COMP 22
Total FN 234
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.661 ± 0.144
Sensitivity 0.538
Positive Predictive Value 0.731
Nr of predictions 15

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L1F_A 0.91 0.83 1.00 20 2060 0 0 0 0 4
2L1F_B 0.92 0.84 1.00 21 2124 0 0 0 0 4
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
2XKV_B 0.38 0.40 0.36 8 4538 23 7 7 9 12
2XXA_G 0.10 0.10 0.11 4 5115 32 1 31 0 38
3IZF_C 0.68 0.56 0.83 30 6867 6 0 6 0 24
3O58_3 0.36 0.34 0.38 12 12371 29 5 15 9 23
3O58_2 0.80 0.68 0.93 26 7232 3 0 2 1 12
3PDR_A 0.72 0.54 0.95 39 12839 4 0 2 2 33
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.62 0.50 0.78 21 3889 6 0 6 0 21
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 23
Total TN 68988
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 483
Total Scores
MCC 0.212
Average MCC ± 95% Confidence Intervals 0.095 ± 0.149
Sensitivity 0.045
Positive Predictive Value 1.000
Nr of predictions 15

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L1F_A 0.00 0.00 0.00 0 2080 0 0 0 0 24
2L1F_B 0.00 0.00 0.00 0 2145 0 0 0 0 25
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.44 0.20 1.00 4 1536 0 0 0 0 16
2XKV_B 0.00 0.00 0.00 0 4560 0 0 0 0 20
2XXA_G 0.00 0.00 0.00 0 5151 0 0 0 0 42
3IZF_C 0.00 0.00 0.00 0 6903 0 0 0 0 54
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3O58_2 0.00 0.00 0.00 0 7260 0 0 0 0 38
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.