CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold Mastr(seed)
MCC 0.640 > 0.263
Average MCC ± 95% Confidence Intervals 0.676 ± 0.106 > 0.093 ± 0.134
Sensitivity 0.553 > 0.070
Positive Predictive Value 0.747 < 1.000
Total TP 372 > 47
Total TN 84273 < 84724
Total FP 151 > 0
Total FP CONTRA 20 > 0
Total FP INCONS 106 > 0
Total FP COMP 25 > 0
Total FN 301 < 626
P-value 5.19332990918e-08

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Performance plots


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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 372
Total TN 84273
Total FP 151
Total FP CONTRA 20
Total FP INCONS 106
Total FP COMP 25
Total FN 301
Total Scores
MCC 0.640
Average MCC ± 95% Confidence Intervals 0.676 ± 0.106
Sensitivity 0.553
Positive Predictive Value 0.747
Nr of predictions 21

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KX8_A 0.94 0.89 1.00 16 845 0 0 0 0 2
2L1F_A 0.91 0.83 1.00 20 2060 0 0 0 0 4
2L1F_B 0.92 0.84 1.00 21 2124 0 0 0 0 4
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
2XKV_B 0.38 0.40 0.36 8 4538 23 7 7 9 12
2XQD_Y 0.81 0.78 0.84 21 2825 4 4 0 0 6
2XXA_G 0.10 0.10 0.11 4 5115 32 1 31 0 38
3AKZ_H 0.66 0.57 0.76 16 2680 6 0 5 1 12
3AMU_B 0.67 0.59 0.76 16 2982 7 0 5 2 11
3IZF_C 0.68 0.56 0.83 30 6867 6 0 6 0 24
3J16_L 0.75 0.57 1.00 17 2758 0 0 0 0 13
3O58_3 0.36 0.34 0.38 12 12371 29 5 15 9 23
3O58_2 0.80 0.68 0.93 26 7232 3 0 2 1 12
3PDR_A 0.72 0.54 0.95 39 12839 4 0 2 2 33
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.62 0.50 0.78 21 3889 6 0 6 0 21
3UZL_B 0.45 0.38 0.54 14 3544 12 1 11 0 23
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 47
Total TN 84724
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 626
Total Scores
MCC 0.263
Average MCC ± 95% Confidence Intervals 0.093 ± 0.134
Sensitivity 0.070
Positive Predictive Value 1.000
Nr of predictions 21

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KX8_A 0.00 0.00 0.00 0 861 0 0 0 0 18
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L94_A 0.00 0.00 0.00 0 990 0 0 0 0 20
2LC8_A 0.00 0.00 0.00 0 1540 0 0 0 0 20
2XKV_B 0.00 0.00 0.00 0 4560 0 0 0 0 20
2XQD_Y 0.00 0.00 0.00 0 2850 0 0 0 0 27
2XXA_G 0.00 0.00 0.00 0 5151 0 0 0 0 42
3AKZ_H 0.00 0.00 0.00 0 2701 0 0 0 0 28
3AMU_B 0.00 0.00 0.00 0 3003 0 0 0 0 27
3IZF_C 0.00 0.00 0.00 0 6903 0 0 0 0 54
3J16_L 0.00 0.00 0.00 0 2775 0 0 0 0 30
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3O58_2 0.00 0.00 0.00 0 7260 0 0 0 0 38
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3UZL_B 0.00 0.00 0.00 0 3570 0 0 0 0 37
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.