CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Fold - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Fold & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Fold Mastr(20)
MCC 0.610 > 0.491
Average MCC ± 95% Confidence Intervals 0.607 ± 0.115 > 0.471 ± 0.154
Sensitivity 0.542 > 0.300
Positive Predictive Value 0.689 < 0.808
Total TP 410 > 227
Total TN 165322 < 165636
Total FP 237 > 65
Total FP CONTRA 24 > 6
Total FP INCONS 161 > 48
Total FP COMP 52 > 11
Total FN 346 < 529
P-value 3.18846395401e-08

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Performance plots


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Performance of Fold - scored higher in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP 410
Total TN 165322
Total FP 237
Total FP CONTRA 24
Total FP INCONS 161
Total FP COMP 52
Total FN 346
Total Scores
MCC 0.610
Average MCC ± 95% Confidence Intervals 0.607 ± 0.115
Sensitivity 0.542
Positive Predictive Value 0.689
Nr of predictions 18

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2. Individual counts for Fold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2XKV_B 0.51 0.50 0.53 10 4541 24 0 9 15 10
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.93 0.86 1.00 36 5115 0 0 0 0 6
3AMU_B 0.64 0.59 0.70 16 2980 9 0 7 2 11
3IZ4_A 0.53 0.46 0.61 61 70776 44 5 34 5 71
3IZF_C 0.70 0.59 0.82 32 6864 7 1 6 0 22
3NPB_A 0.70 0.61 0.80 28 6986 10 1 6 3 18
3O58_3 0.29 0.31 0.28 11 12363 41 3 26 12 24
3O58_2 0.71 0.71 0.71 27 7222 12 3 8 1 11
3PDR_A 0.77 0.64 0.94 46 12831 5 0 3 2 26
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_3 0.68 0.57 0.82 31 7102 7 1 6 0 23
4A1C_2 0.14 0.15 0.14 5 11744 43 5 27 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.32 0.26 0.42 5 1263 7 1 6 0 14
4ENC_A 0.31 0.26 0.38 5 1313 8 1 7 0 14

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 227
Total TN 165636
Total FP 65
Total FP CONTRA 6
Total FP INCONS 48
Total FP COMP 11
Total FN 529
Total Scores
MCC 0.491
Average MCC ± 95% Confidence Intervals 0.471 ± 0.154
Sensitivity 0.300
Positive Predictive Value 0.808
Nr of predictions 18

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.87 0.80 0.94 16 973 1 0 1 0 4
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3AMU_B 0.77 0.59 1.00 16 2987 1 0 0 1 11
3IZ4_A 0.00 0.00 0.00 0 70876 0 0 0 0 132
3IZF_C 0.73 0.63 0.85 34 6863 7 1 5 1 20
3NPB_A 0.30 0.24 0.39 11 6993 18 1 16 1 35
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3O58_2 0.76 0.76 0.76 29 7222 12 3 6 3 9
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.70 0.50 1.00 17 2194 0 0 0 0 17
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
4A1C_3 0.70 0.59 0.84 32 7102 7 0 6 1 22
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.