CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Fold - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Fold & Murlet(20) [.zip] - may take several seconds...


Overview

Metric Fold Murlet(20)
MCC 0.610 > 0.575
Average MCC ± 95% Confidence Intervals 0.607 ± 0.115 > 0.575 ± 0.092
Sensitivity 0.542 > 0.413
Positive Predictive Value 0.689 < 0.804
Total TP 410 > 312
Total TN 165322 < 165529
Total FP 237 > 94
Total FP CONTRA 24 > 7
Total FP INCONS 161 > 69
Total FP COMP 52 > 18
Total FN 346 < 444
P-value 3.82974185391e-08

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Performance plots


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Performance of Fold - scored higher in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP 410
Total TN 165322
Total FP 237
Total FP CONTRA 24
Total FP INCONS 161
Total FP COMP 52
Total FN 346
Total Scores
MCC 0.610
Average MCC ± 95% Confidence Intervals 0.607 ± 0.115
Sensitivity 0.542
Positive Predictive Value 0.689
Nr of predictions 18

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2. Individual counts for Fold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2XKV_B 0.51 0.50 0.53 10 4541 24 0 9 15 10
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.93 0.86 1.00 36 5115 0 0 0 0 6
3AMU_B 0.64 0.59 0.70 16 2980 9 0 7 2 11
3IZ4_A 0.53 0.46 0.61 61 70776 44 5 34 5 71
3IZF_C 0.70 0.59 0.82 32 6864 7 1 6 0 22
3NPB_A 0.70 0.61 0.80 28 6986 10 1 6 3 18
3O58_3 0.29 0.31 0.28 11 12363 41 3 26 12 24
3O58_2 0.71 0.71 0.71 27 7222 12 3 8 1 11
3PDR_A 0.77 0.64 0.94 46 12831 5 0 3 2 26
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_3 0.68 0.57 0.82 31 7102 7 1 6 0 23
4A1C_2 0.14 0.15 0.14 5 11744 43 5 27 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.32 0.26 0.42 5 1263 7 1 6 0 14
4ENC_A 0.31 0.26 0.38 5 1313 8 1 7 0 14

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Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 312
Total TN 165529
Total FP 94
Total FP CONTRA 7
Total FP INCONS 69
Total FP COMP 18
Total FN 444
Total Scores
MCC 0.575
Average MCC ± 95% Confidence Intervals 0.575 ± 0.092
Sensitivity 0.413
Positive Predictive Value 0.804
Nr of predictions 18

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.53 0.50 0.59 10 973 7 0 7 0 10
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XQD_Y 0.80 0.70 0.90 19 2829 2 0 2 0 8
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3AMU_B 0.77 0.67 0.90 18 2983 3 0 2 1 9
3IZ4_A 0.40 0.24 0.65 32 70827 21 1 16 4 100
3IZF_C 0.71 0.56 0.91 30 6870 4 0 3 1 24
3NPB_A 0.55 0.35 0.89 16 7003 2 1 1 0 30
3O58_3 0.33 0.23 0.47 8 12386 12 2 7 3 27
3O58_2 0.89 0.82 0.97 31 7228 2 0 1 1 7
3PDR_A 0.70 0.53 0.93 38 12839 3 0 3 0 34
3RKF_A 0.68 0.47 1.00 16 2195 0 0 0 0 18
3SD1_A 0.68 0.57 0.83 24 3887 5 1 4 0 18
4A1C_3 0.59 0.41 0.85 22 7114 4 0 4 0 32
4A1C_2 0.17 0.15 0.20 5 11756 24 2 18 4 28
4AOB_A 0.72 0.55 0.96 23 4347 2 0 1 1 19
4ENB_A 0.46 0.21 1.00 4 1271 0 0 0 0 15
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.