CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Fold - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Fold & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric Fold Murlet(seed)
MCC 0.648 > 0.542
Average MCC ± 95% Confidence Intervals 0.648 ± 0.151 > 0.553 ± 0.097
Sensitivity 0.588 > 0.339
Positive Predictive Value 0.719 < 0.871
Total TP 340 > 196
Total TN 77689 < 77937
Total FP 178 > 32
Total FP CONTRA 16 > 2
Total FP INCONS 117 > 27
Total FP COMP 45 > 3
Total FN 238 < 382
P-value 2.84041289224e-08

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Performance plots


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Performance of Fold - scored higher in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP 340
Total TN 77689
Total FP 178
Total FP CONTRA 16
Total FP INCONS 117
Total FP COMP 45
Total FN 238
Total Scores
MCC 0.648
Average MCC ± 95% Confidence Intervals 0.648 ± 0.151
Sensitivity 0.588
Positive Predictive Value 0.719
Nr of predictions 19

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2. Individual counts for Fold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KUR_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2KUU_A 0.92 0.86 1.00 18 1110 1 0 0 1 3
2KUV_A 0.93 0.86 1.00 19 1109 0 0 0 0 3
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_A 0.89 0.88 0.91 21 2057 2 0 2 0 3
2L1F_B 0.90 0.88 0.92 22 2121 2 0 2 0 3
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
2XKV_B 0.51 0.50 0.53 10 4541 24 0 9 15 10
2XXA_G 0.93 0.86 1.00 36 5115 0 0 0 0 6
3NPB_A 0.70 0.61 0.80 28 6986 10 1 6 3 18
3O58_3 0.29 0.31 0.28 11 12363 41 3 26 12 24
3PDR_A 0.77 0.64 0.94 46 12831 5 0 3 2 26
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_2 0.14 0.15 0.14 5 11744 43 5 27 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.32 0.26 0.42 5 1263 7 1 6 0 14
4ENC_A 0.31 0.26 0.38 5 1313 8 1 7 0 14

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 196
Total TN 77937
Total FP 32
Total FP CONTRA 2
Total FP INCONS 27
Total FP COMP 3
Total FN 382
Total Scores
MCC 0.542
Average MCC ± 95% Confidence Intervals 0.553 ± 0.097
Sensitivity 0.339
Positive Predictive Value 0.871
Nr of predictions 19

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KUR_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUU_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUV_A 0.85 0.73 1.00 16 1112 0 0 0 0 6
2KUW_A 0.84 0.76 0.94 16 1111 1 0 1 0 5
2L1F_A 0.82 0.75 0.90 18 2060 2 0 2 0 6
2L1F_B 0.80 0.72 0.90 18 2125 2 0 2 0 7
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
2XXA_G 0.38 0.14 1.00 6 5145 0 0 0 0 36
3NPB_A 0.49 0.28 0.87 13 7006 2 1 1 0 33
3O58_3 0.45 0.20 1.00 7 12396 0 0 0 0 28
3PDR_A 0.44 0.19 1.00 14 12866 0 0 0 0 58
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.