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Table of contents:
- Overview
- Performance Plots
- Performance of Fold - scored higher in this pairwise comparison
- Performance of NanoFolder - scored lower in this pairwise comparison
- Compile and download dataset for Fold & NanoFolder [.zip] - may take several seconds...
Overview
| Metric | Fold | NanoFolder | |
|---|---|---|---|
| MCC | 0.629 | > | 0.490 |
| Average MCC ± 95% Confidence Intervals | 0.699 ± 0.163 | > | 0.644 ± 0.159 |
| Sensitivity | 0.559 | > | 0.495 |
| Positive Predictive Value | 0.714 | > | 0.494 |
| Total TP | 227 | > | 201 |
| Total TN | 44687 | > | 44598 |
| Total FP | 106 | < | 218 |
| Total FP CONTRA | 13 | < | 31 |
| Total FP INCONS | 78 | < | 175 |
| Total FP COMP | 15 | > | 12 |
| Total FN | 179 | < | 205 |
| P-value | 2.97012568641e-08 | ||
Performance plots
Performance of Fold - scored higher in this pairwise comparison
1. Total counts & total scores for Fold
| Total Base Pair Counts | |
|---|---|
| Total TP | 227 |
| Total TN | 44687 |
| Total FP | 106 |
| Total FP CONTRA | 13 |
| Total FP INCONS | 78 |
| Total FP COMP | 15 |
| Total FN | 179 |
| Total Scores | |
|---|---|
| MCC | 0.629 |
| Average MCC ± 95% Confidence Intervals | 0.699 ± 0.163 |
| Sensitivity | 0.559 |
| Positive Predictive Value | 0.714 |
| Nr of predictions | 17 |
2. Individual counts for Fold [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1525 | 15 | 2 | 13 | 0 | 20 | |
| 2LDL_A | - | 0.90 | 0.82 | 1.00 | 9 | 342 | 1 | 0 | 0 | 1 | 2 |
| 2LI4_A | - | 0.93 | 0.88 | 1.00 | 14 | 482 | 0 | 0 | 0 | 0 | 2 |
| 2LK3_A | - | 0.95 | 0.90 | 1.00 | 9 | 267 | 0 | 0 | 0 | 0 | 1 |
| 2LKR_A | - | 0.85 | 0.79 | 0.91 | 31 | 6071 | 5 | 0 | 3 | 2 | 8 |
| 2LQZ_A | - | 0.85 | 0.82 | 0.90 | 9 | 341 | 1 | 1 | 0 | 0 | 2 |
| 2LWK_A | - | 0.96 | 0.92 | 1.00 | 12 | 484 | 0 | 0 | 0 | 0 | 1 |
| 3J16_L | 0.63 | 0.53 | 0.76 | 16 | 2754 | 5 | 0 | 5 | 0 | 14 | |
| 3SN2_B | 1.00 | 1.00 | 1.00 | 12 | 394 | 0 | 0 | 0 | 0 | 0 | |
| 3U4M_B | - | 0.45 | 0.35 | 0.59 | 13 | 3138 | 9 | 1 | 8 | 0 | 24 |
| 3UZL_B | 0.77 | 0.62 | 0.96 | 23 | 3546 | 1 | 0 | 1 | 0 | 14 | |
| 3VJR_D | - | 0.96 | 0.92 | 1.00 | 12 | 618 | 0 | 0 | 0 | 0 | 1 |
| 4A1C_3 | 0.68 | 0.57 | 0.82 | 31 | 7102 | 7 | 1 | 6 | 0 | 23 | |
| 4A1C_2 | 0.14 | 0.15 | 0.14 | 5 | 11744 | 43 | 5 | 27 | 11 | 28 | |
| 4A4U_A | - | 1.00 | 1.00 | 1.00 | 9 | 222 | 0 | 0 | 0 | 0 | 0 |
| 4AOB_A | 0.50 | 0.40 | 0.63 | 17 | 4344 | 11 | 2 | 8 | 1 | 25 | |
| 4ENC_A | 0.31 | 0.26 | 0.38 | 5 | 1313 | 8 | 1 | 7 | 0 | 14 |
Performance of NanoFolder - scored lower in this pairwise comparison
1. Total counts & total scores for NanoFolder
| Total Base Pair Counts | |
|---|---|
| Total TP | 201 |
| Total TN | 44598 |
| Total FP | 218 |
| Total FP CONTRA | 31 |
| Total FP INCONS | 175 |
| Total FP COMP | 12 |
| Total FN | 205 |
| Total Scores | |
|---|---|
| MCC | 0.490 |
| Average MCC ± 95% Confidence Intervals | 0.644 ± 0.159 |
| Sensitivity | 0.495 |
| Positive Predictive Value | 0.494 |
| Nr of predictions | 17 |
2. Individual counts for NanoFolder [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2LC8_A | 0.52 | 0.55 | 0.50 | 11 | 1518 | 11 | 0 | 11 | 0 | 9 | |
| 2LDL_A | - | 0.90 | 0.82 | 1.00 | 9 | 342 | 1 | 0 | 0 | 1 | 2 |
| 2LI4_A | - | 0.93 | 0.88 | 1.00 | 14 | 482 | 0 | 0 | 0 | 0 | 2 |
| 2LK3_A | - | 0.95 | 0.90 | 1.00 | 9 | 267 | 0 | 0 | 0 | 0 | 1 |
| 2LKR_A | - | 0.29 | 0.33 | 0.25 | 13 | 6054 | 38 | 8 | 30 | 0 | 26 |
| 2LQZ_A | - | 0.91 | 0.91 | 0.91 | 10 | 340 | 1 | 1 | 0 | 0 | 1 |
| 2LWK_A | - | 0.83 | 0.77 | 0.91 | 10 | 485 | 2 | 0 | 1 | 1 | 3 |
| 3J16_L | 0.36 | 0.37 | 0.37 | 11 | 2745 | 19 | 3 | 16 | 0 | 19 | |
| 3SN2_B | 0.96 | 0.92 | 1.00 | 11 | 395 | 0 | 0 | 0 | 0 | 1 | |
| 3U4M_B | - | 0.61 | 0.57 | 0.66 | 21 | 3128 | 11 | 1 | 10 | 0 | 16 |
| 3UZL_B | 0.36 | 0.35 | 0.38 | 13 | 3536 | 21 | 3 | 18 | 0 | 24 | |
| 3VJR_D | - | 0.96 | 0.92 | 1.00 | 12 | 618 | 0 | 0 | 0 | 0 | 1 |
| 4A1C_3 | 0.48 | 0.46 | 0.51 | 25 | 7091 | 24 | 2 | 22 | 0 | 29 | |
| 4A1C_2 | 0.00 | 0.00 | 0.00 | 0 | 11728 | 61 | 12 | 41 | 8 | 33 | |
| 4A4U_A | - | 1.00 | 1.00 | 1.00 | 9 | 222 | 0 | 0 | 0 | 0 | 0 |
| 4AOB_A | 0.33 | 0.29 | 0.39 | 12 | 4340 | 20 | 1 | 18 | 1 | 30 | |
| 4ENC_A | 0.57 | 0.58 | 0.58 | 11 | 1307 | 9 | 0 | 8 | 1 | 8 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.