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Table of contents:
- Overview
- Performance Plots
- Performance of MXScarna(20) - scored higher in this pairwise comparison
- Performance of Pknots - scored lower in this pairwise comparison
- Compile and download dataset for MXScarna(20) & Pknots [.zip] - may take several seconds...
Overview
| Metric | MXScarna(20) | Pknots | |
|---|---|---|---|
| MCC | 0.644 | > | 0.530 |
| Average MCC ± 95% Confidence Intervals | 0.641 ± 0.072 | > | 0.581 ± 0.107 |
| Sensitivity | 0.540 | > | 0.483 |
| Positive Predictive Value | 0.773 | > | 0.589 |
| Total TP | 504 | > | 451 |
| Total TN | 138578 | > | 138464 |
| Total FP | 231 | < | 364 |
| Total FP CONTRA | 24 | < | 52 |
| Total FP INCONS | 124 | < | 263 |
| Total FP COMP | 83 | > | 49 |
| Total FN | 430 | < | 483 |
| P-value | 5.23657817852e-08 | ||
Performance plots
Performance of MXScarna(20) - scored higher in this pairwise comparison
1. Total counts & total scores for MXScarna(20)
| Total Base Pair Counts | |
|---|---|
| Total TP | 504 |
| Total TN | 138578 |
| Total FP | 231 |
| Total FP CONTRA | 24 |
| Total FP INCONS | 124 |
| Total FP COMP | 83 |
| Total FN | 430 |
| Total Scores | |
|---|---|
| MCC | 0.644 |
| Average MCC ± 95% Confidence Intervals | 0.641 ± 0.072 |
| Sensitivity | 0.540 |
| Positive Predictive Value | 0.773 |
| Nr of predictions | 27 |
2. Individual counts for MXScarna(20) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2L94_A | 0.73 | 0.70 | 0.78 | 14 | 972 | 4 | 0 | 4 | 0 | 6 | |
| 2WRQ_Y | 0.57 | 0.59 | 0.56 | 10 | 2832 | 13 | 5 | 3 | 5 | 7 | |
| 2XKV_B | 0.45 | 0.20 | 1.00 | 4 | 4556 | 3 | 0 | 0 | 3 | 16 | |
| 2XQD_Y | 0.88 | 0.78 | 1.00 | 21 | 2829 | 0 | 0 | 0 | 0 | 6 | |
| 2XXA_G | 0.80 | 0.71 | 0.91 | 30 | 5118 | 4 | 0 | 3 | 1 | 12 | |
| 3A2K_C | 0.66 | 0.57 | 0.76 | 16 | 2905 | 6 | 1 | 4 | 1 | 12 | |
| 3AMU_B | 0.86 | 0.74 | 1.00 | 20 | 2983 | 2 | 0 | 0 | 2 | 7 | |
| 3G4S_9 | 0.52 | 0.40 | 0.68 | 23 | 7347 | 13 | 1 | 10 | 2 | 34 | |
| 3GX2_A | 0.70 | 0.58 | 0.85 | 23 | 4344 | 5 | 0 | 4 | 1 | 17 | |
| 3IVN_B | 0.74 | 0.58 | 0.95 | 18 | 2327 | 1 | 1 | 0 | 0 | 13 | |
| 3IZF_C | 0.67 | 0.59 | 0.76 | 32 | 6861 | 11 | 1 | 9 | 1 | 22 | |
| 3JYV_7 | 0.79 | 0.63 | 1.00 | 20 | 2830 | 0 | 0 | 0 | 0 | 12 | |
| 3JYX_3 | 0.55 | 0.52 | 0.58 | 14 | 6304 | 23 | 0 | 10 | 13 | 13 | |
| 3JYX_4 | 0.33 | 0.30 | 0.37 | 10 | 12219 | 32 | 2 | 15 | 15 | 23 | |
| 3LA5_A | 0.78 | 0.62 | 1.00 | 21 | 2464 | 0 | 0 | 0 | 0 | 13 | |
| 3NPB_A | 0.69 | 0.59 | 0.82 | 27 | 6988 | 9 | 1 | 5 | 3 | 19 | |
| 3O58_2 | 0.74 | 0.74 | 0.74 | 28 | 7222 | 13 | 4 | 6 | 3 | 10 | |
| 3O58_3 | 0.52 | 0.40 | 0.67 | 14 | 12382 | 17 | 2 | 5 | 10 | 21 | |
| 3PDR_A | 0.71 | 0.57 | 0.89 | 41 | 12834 | 9 | 0 | 5 | 4 | 31 | |
| 3RKF_A | 0.72 | 0.53 | 1.00 | 18 | 2193 | 0 | 0 | 0 | 0 | 16 | |
| 3SD1_A | 0.63 | 0.55 | 0.74 | 23 | 3885 | 8 | 2 | 6 | 0 | 19 | |
| 4A1C_3 | 0.64 | 0.56 | 0.75 | 30 | 7100 | 11 | 2 | 8 | 1 | 24 | |
| 4A1C_2 | 0.18 | 0.15 | 0.21 | 5 | 11757 | 36 | 2 | 17 | 17 | 28 | |
| 4AOB_A | 0.62 | 0.55 | 0.72 | 23 | 4339 | 10 | 0 | 9 | 1 | 19 | |
| 4ENB_A | 0.26 | 0.11 | 0.67 | 2 | 1272 | 1 | 0 | 1 | 0 | 17 | |
| 4ENC_A | 0.60 | 0.37 | 1.00 | 7 | 1319 | 0 | 0 | 0 | 0 | 12 |
Performance of Pknots - scored lower in this pairwise comparison
1. Total counts & total scores for Pknots
| Total Base Pair Counts | |
|---|---|
| Total TP | 451 |
| Total TN | 138464 |
| Total FP | 364 |
| Total FP CONTRA | 52 |
| Total FP INCONS | 263 |
| Total FP COMP | 49 |
| Total FN | 483 |
| Total Scores | |
|---|---|
| MCC | 0.530 |
| Average MCC ± 95% Confidence Intervals | 0.581 ± 0.107 |
| Sensitivity | 0.483 |
| Positive Predictive Value | 0.589 |
| Nr of predictions | 27 |
2. Individual counts for Pknots [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2L94_A | 0.92 | 0.90 | 0.95 | 18 | 971 | 1 | 0 | 1 | 0 | 2 | |
| 2WRQ_Y | 0.57 | 0.59 | 0.56 | 10 | 2832 | 12 | 5 | 3 | 4 | 7 | |
| 2XKV_B | 0.23 | 0.25 | 0.22 | 5 | 4537 | 31 | 1 | 17 | 13 | 15 | |
| 2XQD_Y | 0.88 | 0.78 | 1.00 | 21 | 2829 | 0 | 0 | 0 | 0 | 6 | |
| 2XXA_G | 0.32 | 0.31 | 0.34 | 13 | 5113 | 25 | 1 | 24 | 0 | 29 | |
| 3A2K_C | 0.45 | 0.43 | 0.48 | 12 | 2901 | 13 | 2 | 11 | 0 | 16 | |
| 3AMU_B | 0.86 | 0.74 | 1.00 | 20 | 2983 | 2 | 0 | 0 | 2 | 7 | |
| 3G4S_9 | 0.25 | 0.21 | 0.31 | 12 | 7342 | 27 | 0 | 27 | 0 | 45 | |
| 3GX2_A | 0.47 | 0.40 | 0.55 | 16 | 4342 | 14 | 1 | 12 | 1 | 24 | |
| 3IVN_B | 0.78 | 0.65 | 0.95 | 20 | 2325 | 1 | 0 | 1 | 0 | 11 | |
| 3IZF_C | 0.70 | 0.61 | 0.80 | 33 | 6862 | 8 | 1 | 7 | 0 | 21 | |
| 3JYV_7 | 0.81 | 0.66 | 1.00 | 21 | 2829 | 0 | 0 | 0 | 0 | 11 | |
| 3JYX_3 | 0.34 | 0.37 | 0.31 | 10 | 6296 | 24 | 9 | 13 | 2 | 17 | |
| 3JYX_4 | 0.18 | 0.21 | 0.16 | 7 | 12203 | 41 | 13 | 23 | 5 | 26 | |
| 3LA5_A | 0.80 | 0.65 | 1.00 | 22 | 2463 | 0 | 0 | 0 | 0 | 12 | |
| 3NPB_A | 0.76 | 0.67 | 0.86 | 31 | 6985 | 8 | 1 | 4 | 3 | 15 | |
| 3O58_2 | 0.83 | 0.74 | 0.93 | 28 | 7230 | 3 | 0 | 2 | 1 | 10 | |
| 3O58_3 | 0.27 | 0.31 | 0.24 | 11 | 12357 | 38 | 11 | 24 | 3 | 24 | |
| 3PDR_A | 0.54 | 0.44 | 0.65 | 32 | 12831 | 19 | 0 | 17 | 2 | 40 | |
| 3RKF_A | 0.77 | 0.62 | 0.95 | 21 | 2189 | 1 | 0 | 1 | 0 | 13 | |
| 3SD1_A | 0.65 | 0.52 | 0.81 | 22 | 3889 | 5 | 0 | 5 | 0 | 20 | |
| 4A1C_3 | 0.25 | 0.22 | 0.29 | 12 | 7099 | 29 | 1 | 28 | 0 | 42 | |
| 4A1C_2 | 0.24 | 0.24 | 0.25 | 8 | 11749 | 36 | 3 | 21 | 12 | 25 | |
| 4AOB_A | 0.17 | 0.14 | 0.21 | 6 | 4343 | 23 | 1 | 21 | 1 | 36 | |
| 4ENB_A | 0.83 | 0.79 | 0.88 | 15 | 1258 | 2 | 1 | 1 | 0 | 4 | |
| 4ENC_A | 0.86 | 0.79 | 0.94 | 15 | 1310 | 1 | 1 | 0 | 0 | 4 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.