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Table of contents:
- Overview
- Performance Plots
- Performance of MXScarna(20) - scored higher in this pairwise comparison
- Performance of ProbKnot - scored lower in this pairwise comparison
- Compile and download dataset for MXScarna(20) & ProbKnot [.zip] - may take several seconds...
Overview
| Metric | MXScarna(20) | ProbKnot | |
|---|---|---|---|
| MCC | 0.628 | > | 0.586 |
| Average MCC ± 95% Confidence Intervals | 0.624 ± 0.093 | > | 0.605 ± 0.109 |
| Sensitivity | 0.520 | < | 0.529 |
| Positive Predictive Value | 0.762 | > | 0.653 |
| Total TP | 393 | < | 400 |
| Total TN | 165401 | > | 165304 |
| Total FP | 170 | < | 267 |
| Total FP CONTRA | 21 | < | 31 |
| Total FP INCONS | 102 | < | 182 |
| Total FP COMP | 47 | < | 54 |
| Total FN | 363 | > | 356 |
| P-value | 3.54229534325e-08 | ||
Performance plots
Performance of MXScarna(20) - scored higher in this pairwise comparison
1. Total counts & total scores for MXScarna(20)
| Total Base Pair Counts | |
|---|---|
| Total TP | 393 |
| Total TN | 165401 |
| Total FP | 170 |
| Total FP CONTRA | 21 |
| Total FP INCONS | 102 |
| Total FP COMP | 47 |
| Total FN | 363 |
| Total Scores | |
|---|---|
| MCC | 0.628 |
| Average MCC ± 95% Confidence Intervals | 0.624 ± 0.093 |
| Sensitivity | 0.520 |
| Positive Predictive Value | 0.762 |
| Nr of predictions | 18 |
2. Individual counts for MXScarna(20) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2L94_A | 0.73 | 0.70 | 0.78 | 14 | 972 | 4 | 0 | 4 | 0 | 6 | |
| 2XKV_B | 0.45 | 0.20 | 1.00 | 4 | 4556 | 3 | 0 | 0 | 3 | 16 | |
| 2XQD_Y | 0.88 | 0.78 | 1.00 | 21 | 2829 | 0 | 0 | 0 | 0 | 6 | |
| 2XXA_G | 0.80 | 0.71 | 0.91 | 30 | 5118 | 4 | 0 | 3 | 1 | 12 | |
| 3AMU_B | 0.86 | 0.74 | 1.00 | 20 | 2983 | 2 | 0 | 0 | 2 | 7 | |
| 3IZ4_A | 0.51 | 0.41 | 0.64 | 54 | 70791 | 32 | 7 | 24 | 1 | 78 | |
| 3IZF_C | 0.67 | 0.59 | 0.76 | 32 | 6861 | 11 | 1 | 9 | 1 | 22 | |
| 3NPB_A | 0.69 | 0.59 | 0.82 | 27 | 6988 | 9 | 1 | 5 | 3 | 19 | |
| 3O58_3 | 0.52 | 0.40 | 0.67 | 14 | 12382 | 17 | 2 | 5 | 10 | 21 | |
| 3O58_2 | 0.74 | 0.74 | 0.74 | 28 | 7222 | 13 | 4 | 6 | 3 | 10 | |
| 3PDR_A | 0.71 | 0.57 | 0.89 | 41 | 12834 | 9 | 0 | 5 | 4 | 31 | |
| 3RKF_A | 0.72 | 0.53 | 1.00 | 18 | 2193 | 0 | 0 | 0 | 0 | 16 | |
| 3SD1_A | 0.63 | 0.55 | 0.74 | 23 | 3885 | 8 | 2 | 6 | 0 | 19 | |
| 4A1C_3 | 0.64 | 0.56 | 0.75 | 30 | 7100 | 11 | 2 | 8 | 1 | 24 | |
| 4A1C_2 | 0.18 | 0.15 | 0.21 | 5 | 11757 | 36 | 2 | 17 | 17 | 28 | |
| 4AOB_A | 0.62 | 0.55 | 0.72 | 23 | 4339 | 10 | 0 | 9 | 1 | 19 | |
| 4ENB_A | 0.26 | 0.11 | 0.67 | 2 | 1272 | 1 | 0 | 1 | 0 | 17 | |
| 4ENC_A | 0.60 | 0.37 | 1.00 | 7 | 1319 | 0 | 0 | 0 | 0 | 12 |
Performance of ProbKnot - scored lower in this pairwise comparison
1. Total counts & total scores for ProbKnot
| Total Base Pair Counts | |
|---|---|
| Total TP | 400 |
| Total TN | 165304 |
| Total FP | 267 |
| Total FP CONTRA | 31 |
| Total FP INCONS | 182 |
| Total FP COMP | 54 |
| Total FN | 356 |
| Total Scores | |
|---|---|
| MCC | 0.586 |
| Average MCC ± 95% Confidence Intervals | 0.605 ± 0.109 |
| Sensitivity | 0.529 |
| Positive Predictive Value | 0.653 |
| Nr of predictions | 18 |
2. Individual counts for ProbKnot [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2XKV_B | 0.51 | 0.50 | 0.53 | 10 | 4541 | 24 | 0 | 9 | 15 | 10 | |
| 2XQD_Y | 0.90 | 0.81 | 1.00 | 22 | 2828 | 1 | 0 | 0 | 1 | 5 | |
| 2XXA_G | 0.26 | 0.24 | 0.29 | 10 | 5116 | 25 | 1 | 24 | 0 | 32 | |
| 3AMU_B | 0.65 | 0.59 | 0.73 | 16 | 2981 | 8 | 0 | 6 | 2 | 11 | |
| 3IZ4_A | 0.52 | 0.46 | 0.60 | 61 | 70774 | 46 | 6 | 35 | 5 | 71 | |
| 3IZF_C | 0.72 | 0.61 | 0.85 | 33 | 6864 | 6 | 0 | 6 | 0 | 21 | |
| 3NPB_A | 0.72 | 0.61 | 0.85 | 28 | 6988 | 8 | 1 | 4 | 3 | 18 | |
| 3O58_3 | 0.31 | 0.34 | 0.29 | 12 | 12362 | 41 | 4 | 25 | 12 | 23 | |
| 3O58_2 | 0.76 | 0.76 | 0.76 | 29 | 7222 | 10 | 3 | 6 | 1 | 9 | |
| 3PDR_A | 0.74 | 0.64 | 0.85 | 46 | 12826 | 10 | 1 | 7 | 2 | 26 | |
| 3RKF_A | 0.73 | 0.59 | 0.91 | 20 | 2189 | 2 | 1 | 1 | 0 | 14 | |
| 3SD1_A | 0.55 | 0.48 | 0.65 | 20 | 3885 | 11 | 2 | 9 | 0 | 22 | |
| 4A1C_3 | 0.73 | 0.61 | 0.87 | 33 | 7102 | 6 | 1 | 4 | 1 | 21 | |
| 4A1C_2 | 0.13 | 0.15 | 0.12 | 5 | 11738 | 49 | 7 | 31 | 11 | 28 | |
| 4AOB_A | 0.50 | 0.40 | 0.63 | 17 | 4344 | 11 | 2 | 8 | 1 | 25 | |
| 4ENB_A | 0.73 | 0.58 | 0.92 | 11 | 1263 | 1 | 1 | 0 | 0 | 8 | |
| 4ENC_A | 0.45 | 0.42 | 0.50 | 8 | 1310 | 8 | 1 | 7 | 0 | 11 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.