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Table of contents:
- Overview
- Performance Plots
- Performance of MXScarna(seed) - scored higher in this pairwise comparison
- Performance of Alterna - scored lower in this pairwise comparison
- Compile and download dataset for MXScarna(seed) & Alterna [.zip] - may take several seconds...
Overview
| Metric | MXScarna(seed) | Alterna | |
|---|---|---|---|
| MCC | 0.725 | > | 0.655 |
| Average MCC ± 95% Confidence Intervals | 0.709 ± 0.088 | > | 0.681 ± 0.099 |
| Sensitivity | 0.609 | > | 0.587 |
| Positive Predictive Value | 0.869 | > | 0.737 |
| Total TP | 471 | > | 454 |
| Total TN | 69086 | > | 69012 |
| Total FP | 94 | < | 188 |
| Total FP CONTRA | 12 | < | 20 |
| Total FP INCONS | 59 | < | 142 |
| Total FP COMP | 23 | < | 26 |
| Total FN | 302 | < | 319 |
| P-value | 5.19332990918e-08 | ||
Performance plots
Performance of MXScarna(seed) - scored higher in this pairwise comparison
1. Total counts & total scores for MXScarna(seed)
| Total Base Pair Counts | |
|---|---|
| Total TP | 471 |
| Total TN | 69086 |
| Total FP | 94 |
| Total FP CONTRA | 12 |
| Total FP INCONS | 59 |
| Total FP COMP | 23 |
| Total FN | 302 |
| Total Scores | |
|---|---|
| MCC | 0.725 |
| Average MCC ± 95% Confidence Intervals | 0.709 ± 0.088 |
| Sensitivity | 0.609 |
| Positive Predictive Value | 0.869 |
| Nr of predictions | 29 |
2. Individual counts for MXScarna(seed) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2KE6_A | 0.89 | 0.84 | 0.94 | 16 | 1111 | 2 | 0 | 1 | 1 | 3 | |
| 2KUR_A | 0.87 | 0.81 | 0.94 | 17 | 1110 | 1 | 0 | 1 | 0 | 4 | |
| 2KUU_A | 0.84 | 0.76 | 0.94 | 16 | 1111 | 2 | 0 | 1 | 1 | 5 | |
| 2KUV_A | 0.85 | 0.77 | 0.94 | 17 | 1110 | 1 | 0 | 1 | 0 | 5 | |
| 2KUW_A | 0.76 | 0.67 | 0.88 | 14 | 1112 | 2 | 0 | 2 | 0 | 7 | |
| 2KX8_A | -0.01 | 0.00 | 0.00 | 0 | 859 | 2 | 0 | 2 | 0 | 18 | |
| 2L1F_A | 0.91 | 0.88 | 0.95 | 21 | 2058 | 1 | 0 | 1 | 0 | 3 | |
| 2L1F_B | 0.96 | 0.92 | 1.00 | 23 | 2122 | 0 | 0 | 0 | 0 | 2 | |
| 2L94_A | 0.57 | 0.55 | 0.61 | 11 | 972 | 7 | 0 | 7 | 0 | 9 | |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1530 | 12 | 0 | 10 | 2 | 20 | |
| 2WRQ_Y | 0.57 | 0.59 | 0.56 | 10 | 2832 | 11 | 5 | 3 | 3 | 7 | |
| 2WWQ_V | 0.56 | 0.46 | 0.68 | 13 | 2907 | 7 | 0 | 6 | 1 | 15 | |
| 2XKV_B | 0.59 | 0.55 | 0.65 | 11 | 4543 | 18 | 0 | 6 | 12 | 9 | |
| 2XQD_Y | 0.77 | 0.67 | 0.90 | 18 | 2830 | 2 | 0 | 2 | 0 | 9 | |
| 2ZZM_B | 0.56 | 0.44 | 0.74 | 14 | 3467 | 5 | 4 | 1 | 0 | 18 | |
| 2ZZN_D | 0.86 | 0.74 | 1.00 | 20 | 2465 | 0 | 0 | 0 | 0 | 7 | |
| 3A2K_C | 0.84 | 0.71 | 1.00 | 20 | 2906 | 0 | 0 | 0 | 0 | 8 | |
| 3A3A_A | 0.77 | 0.65 | 0.92 | 24 | 3629 | 3 | 0 | 2 | 1 | 13 | |
| 3AKZ_H | 0.86 | 0.75 | 1.00 | 21 | 2680 | 0 | 0 | 0 | 0 | 7 | |
| 3AMU_B | 0.84 | 0.70 | 1.00 | 19 | 2984 | 1 | 0 | 0 | 1 | 8 | |
| 3GX2_A | 0.70 | 0.60 | 0.83 | 24 | 4342 | 6 | 0 | 5 | 1 | 16 | |
| 3IVN_B | 0.65 | 0.45 | 0.93 | 14 | 2331 | 1 | 1 | 0 | 0 | 17 | |
| 3J16_L | 0.82 | 0.67 | 1.00 | 20 | 2755 | 0 | 0 | 0 | 0 | 10 | |
| 3JYV_7 | 0.79 | 0.63 | 1.00 | 20 | 2830 | 0 | 0 | 0 | 0 | 12 | |
| 3LA5_A | 0.75 | 0.56 | 1.00 | 19 | 2466 | 0 | 0 | 0 | 0 | 15 | |
| 3RKF_A | 0.72 | 0.53 | 1.00 | 18 | 2193 | 0 | 0 | 0 | 0 | 16 | |
| 3SD1_A | 0.63 | 0.55 | 0.74 | 23 | 3885 | 8 | 1 | 7 | 0 | 19 | |
| 3UZL_B | 0.66 | 0.49 | 0.90 | 18 | 3550 | 2 | 1 | 1 | 0 | 19 |
Performance of Alterna - scored lower in this pairwise comparison
1. Total counts & total scores for Alterna
| Total Base Pair Counts | |
|---|---|
| Total TP | 454 |
| Total TN | 69012 |
| Total FP | 188 |
| Total FP CONTRA | 20 |
| Total FP INCONS | 142 |
| Total FP COMP | 26 |
| Total FN | 319 |
| Total Scores | |
|---|---|
| MCC | 0.655 |
| Average MCC ± 95% Confidence Intervals | 0.681 ± 0.099 |
| Sensitivity | 0.587 |
| Positive Predictive Value | 0.737 |
| Nr of predictions | 29 |
2. Individual counts for Alterna [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2KE6_A | 0.92 | 0.89 | 0.94 | 17 | 1110 | 2 | 0 | 1 | 1 | 2 | |
| 2KUR_A | 0.90 | 0.86 | 0.95 | 18 | 1109 | 1 | 0 | 1 | 0 | 3 | |
| 2KUU_A | 0.87 | 0.81 | 0.94 | 17 | 1110 | 2 | 0 | 1 | 1 | 4 | |
| 2KUV_A | 0.88 | 0.82 | 0.95 | 18 | 1109 | 1 | 0 | 1 | 0 | 4 | |
| 2KUW_A | 0.95 | 0.90 | 1.00 | 19 | 1109 | 0 | 0 | 0 | 0 | 2 | |
| 2KX8_A | 0.88 | 0.83 | 0.94 | 15 | 845 | 1 | 0 | 1 | 0 | 3 | |
| 2L1F_A | 0.98 | 0.96 | 1.00 | 23 | 2057 | 0 | 0 | 0 | 0 | 1 | |
| 2L1F_B | 0.98 | 0.96 | 1.00 | 24 | 2121 | 0 | 0 | 0 | 0 | 1 | |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2LC8_A | 0.46 | 0.40 | 0.53 | 8 | 1525 | 7 | 0 | 7 | 0 | 12 | |
| 2WRQ_Y | 0.57 | 0.59 | 0.56 | 10 | 2832 | 13 | 5 | 3 | 5 | 7 | |
| 2WWQ_V | 0.76 | 0.68 | 0.86 | 19 | 2904 | 5 | 0 | 3 | 2 | 9 | |
| 2XKV_B | 0.45 | 0.45 | 0.45 | 9 | 4540 | 25 | 0 | 11 | 14 | 11 | |
| 2XQD_Y | 0.67 | 0.59 | 0.76 | 16 | 2829 | 5 | 0 | 5 | 0 | 11 | |
| 2ZZM_B | 0.10 | 0.09 | 0.13 | 3 | 3463 | 20 | 2 | 18 | 0 | 29 | |
| 2ZZN_D | 0.84 | 0.78 | 0.91 | 21 | 2462 | 2 | 0 | 2 | 0 | 6 | |
| 3A2K_C | 0.44 | 0.43 | 0.46 | 12 | 2900 | 14 | 2 | 12 | 0 | 16 | |
| 3A3A_A | 0.84 | 0.70 | 1.00 | 26 | 3629 | 0 | 0 | 0 | 0 | 11 | |
| 3AKZ_H | 0.40 | 0.39 | 0.42 | 11 | 2675 | 15 | 4 | 11 | 0 | 17 | |
| 3AMU_B | 0.64 | 0.59 | 0.70 | 16 | 2980 | 9 | 0 | 7 | 2 | 11 | |
| 3GX2_A | 0.47 | 0.40 | 0.57 | 16 | 4343 | 13 | 1 | 11 | 1 | 24 | |
| 3IVN_B | 0.74 | 0.61 | 0.90 | 19 | 2325 | 2 | 1 | 1 | 0 | 12 | |
| 3J16_L | 0.63 | 0.53 | 0.76 | 16 | 2754 | 5 | 1 | 4 | 0 | 14 | |
| 3JYV_7 | -0.01 | 0.00 | 0.00 | 0 | 2828 | 22 | 0 | 22 | 0 | 32 | |
| 3LA5_A | 0.78 | 0.62 | 1.00 | 21 | 2464 | 0 | 0 | 0 | 0 | 13 | |
| 3RKF_A | 0.69 | 0.56 | 0.86 | 19 | 2189 | 3 | 1 | 2 | 0 | 15 | |
| 3SD1_A | 0.46 | 0.38 | 0.57 | 16 | 3888 | 12 | 1 | 11 | 0 | 26 | |
| 3UZL_B | 0.52 | 0.43 | 0.64 | 16 | 3545 | 9 | 2 | 7 | 0 | 21 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.