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Table of contents:
- Overview
- Performance Plots
- Performance of MXScarna(seed) - scored higher in this pairwise comparison
- Performance of Cylofold - scored lower in this pairwise comparison
- Compile and download dataset for MXScarna(seed) & Cylofold [.zip] - may take several seconds...
Overview
| Metric | MXScarna(seed) | Cylofold | |
|---|---|---|---|
| MCC | 0.676 | > | 0.640 |
| Average MCC ± 95% Confidence Intervals | 0.630 ± 0.116 | < | 0.676 ± 0.106 |
| Sensitivity | 0.565 | > | 0.553 |
| Positive Predictive Value | 0.814 | > | 0.747 |
| Total TP | 380 | > | 372 |
| Total TN | 84304 | > | 84273 |
| Total FP | 120 | < | 151 |
| Total FP CONTRA | 12 | < | 20 |
| Total FP INCONS | 75 | < | 106 |
| Total FP COMP | 33 | > | 25 |
| Total FN | 293 | < | 301 |
| P-value | 5.32337795675e-08 | ||
Performance plots
Performance of MXScarna(seed) - scored higher in this pairwise comparison
1. Total counts & total scores for MXScarna(seed)
| Total Base Pair Counts | |
|---|---|
| Total TP | 380 |
| Total TN | 84304 |
| Total FP | 120 |
| Total FP CONTRA | 12 |
| Total FP INCONS | 75 |
| Total FP COMP | 33 |
| Total FN | 293 |
| Total Scores | |
|---|---|
| MCC | 0.676 |
| Average MCC ± 95% Confidence Intervals | 0.630 ± 0.116 |
| Sensitivity | 0.565 |
| Positive Predictive Value | 0.814 |
| Nr of predictions | 21 |
2. Individual counts for MXScarna(seed) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KX8_A | -0.01 | 0.00 | 0.00 | 0 | 859 | 2 | 0 | 2 | 0 | 18 | |
| 2L1F_A | 0.91 | 0.88 | 0.95 | 21 | 2058 | 1 | 0 | 1 | 0 | 3 | |
| 2L1F_B | 0.96 | 0.92 | 1.00 | 23 | 2122 | 0 | 0 | 0 | 0 | 2 | |
| 2L94_A | 0.57 | 0.55 | 0.61 | 11 | 972 | 7 | 0 | 7 | 0 | 9 | |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1530 | 12 | 0 | 10 | 2 | 20 | |
| 2XKV_B | 0.59 | 0.55 | 0.65 | 11 | 4543 | 18 | 0 | 6 | 12 | 9 | |
| 2XQD_Y | 0.77 | 0.67 | 0.90 | 18 | 2830 | 2 | 0 | 2 | 0 | 9 | |
| 2XXA_G | 0.67 | 0.57 | 0.80 | 24 | 5121 | 7 | 0 | 6 | 1 | 18 | |
| 3AKZ_H | 0.86 | 0.75 | 1.00 | 21 | 2680 | 0 | 0 | 0 | 0 | 7 | |
| 3AMU_B | 0.84 | 0.70 | 1.00 | 19 | 2984 | 1 | 0 | 0 | 1 | 8 | |
| 3IZF_C | 0.67 | 0.57 | 0.79 | 31 | 6864 | 9 | 1 | 7 | 1 | 23 | |
| 3J16_L | 0.82 | 0.67 | 1.00 | 20 | 2755 | 0 | 0 | 0 | 0 | 10 | |
| 3O58_3 | 0.45 | 0.34 | 0.60 | 12 | 12383 | 19 | 2 | 6 | 11 | 23 | |
| 3O58_2 | 0.79 | 0.79 | 0.79 | 30 | 7222 | 10 | 4 | 4 | 2 | 8 | |
| 3PDR_A | 0.73 | 0.63 | 0.87 | 45 | 12828 | 9 | 2 | 5 | 2 | 27 | |
| 3RKF_A | 0.72 | 0.53 | 1.00 | 18 | 2193 | 0 | 0 | 0 | 0 | 16 | |
| 3SD1_A | 0.63 | 0.55 | 0.74 | 23 | 3885 | 8 | 1 | 7 | 0 | 19 | |
| 3UZL_B | 0.66 | 0.49 | 0.90 | 18 | 3550 | 2 | 1 | 1 | 0 | 19 | |
| 4AOB_A | 0.66 | 0.55 | 0.79 | 23 | 4342 | 7 | 0 | 6 | 1 | 19 | |
| 4ENB_A | 0.48 | 0.32 | 0.75 | 6 | 1267 | 2 | 0 | 2 | 0 | 13 | |
| 4ENC_A | 0.43 | 0.32 | 0.60 | 6 | 1316 | 4 | 1 | 3 | 0 | 13 |
Performance of Cylofold - scored lower in this pairwise comparison
1. Total counts & total scores for Cylofold
| Total Base Pair Counts | |
|---|---|
| Total TP | 372 |
| Total TN | 84273 |
| Total FP | 151 |
| Total FP CONTRA | 20 |
| Total FP INCONS | 106 |
| Total FP COMP | 25 |
| Total FN | 301 |
| Total Scores | |
|---|---|
| MCC | 0.640 |
| Average MCC ± 95% Confidence Intervals | 0.676 ± 0.106 |
| Sensitivity | 0.553 |
| Positive Predictive Value | 0.747 |
| Nr of predictions | 21 |
2. Individual counts for Cylofold [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KX8_A | 0.94 | 0.89 | 1.00 | 16 | 845 | 0 | 0 | 0 | 0 | 2 | |
| 2L1F_A | 0.91 | 0.83 | 1.00 | 20 | 2060 | 0 | 0 | 0 | 0 | 4 | |
| 2L1F_B | 0.92 | 0.84 | 1.00 | 21 | 2124 | 0 | 0 | 0 | 0 | 4 | |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2LC8_A | 0.61 | 0.55 | 0.69 | 11 | 1524 | 5 | 0 | 5 | 0 | 9 | |
| 2XKV_B | 0.38 | 0.40 | 0.36 | 8 | 4538 | 23 | 7 | 7 | 9 | 12 | |
| 2XQD_Y | 0.81 | 0.78 | 0.84 | 21 | 2825 | 4 | 4 | 0 | 0 | 6 | |
| 2XXA_G | 0.10 | 0.10 | 0.11 | 4 | 5115 | 32 | 1 | 31 | 0 | 38 | |
| 3AKZ_H | 0.66 | 0.57 | 0.76 | 16 | 2680 | 6 | 0 | 5 | 1 | 12 | |
| 3AMU_B | 0.67 | 0.59 | 0.76 | 16 | 2982 | 7 | 0 | 5 | 2 | 11 | |
| 3IZF_C | 0.68 | 0.56 | 0.83 | 30 | 6867 | 6 | 0 | 6 | 0 | 24 | |
| 3J16_L | 0.75 | 0.57 | 1.00 | 17 | 2758 | 0 | 0 | 0 | 0 | 13 | |
| 3O58_3 | 0.36 | 0.34 | 0.38 | 12 | 12371 | 29 | 5 | 15 | 9 | 23 | |
| 3O58_2 | 0.80 | 0.68 | 0.93 | 26 | 7232 | 3 | 0 | 2 | 1 | 12 | |
| 3PDR_A | 0.72 | 0.54 | 0.95 | 39 | 12839 | 4 | 0 | 2 | 2 | 33 | |
| 3RKF_A | 0.76 | 0.59 | 1.00 | 20 | 2191 | 0 | 0 | 0 | 0 | 14 | |
| 3SD1_A | 0.62 | 0.50 | 0.78 | 21 | 3889 | 6 | 0 | 6 | 0 | 21 | |
| 3UZL_B | 0.45 | 0.38 | 0.54 | 14 | 3544 | 12 | 1 | 11 | 0 | 23 | |
| 4AOB_A | 0.35 | 0.26 | 0.48 | 11 | 4348 | 13 | 1 | 11 | 1 | 31 | |
| 4ENB_A | 0.89 | 0.79 | 1.00 | 15 | 1260 | 0 | 0 | 0 | 0 | 4 | |
| 4ENC_A | 0.86 | 0.79 | 0.94 | 15 | 1310 | 1 | 1 | 0 | 0 | 4 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.