CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold5 - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & Vsfold5 [.zip] - may take several seconds...


Overview

Metric Mastr(20) Vsfold5
MCC 0.525 > 0.406
Average MCC ± 95% Confidence Intervals 0.518 ± 0.116 > 0.458 ± 0.126
Sensitivity 0.346 < 0.347
Positive Predictive Value 0.800 > 0.481
Total TP 369 < 370
Total TN 209645 > 209336
Total FP 122 < 451
Total FP CONTRA 14 < 52
Total FP INCONS 78 < 348
Total FP COMP 30 < 51
Total FN 697 > 696
P-value 5.1503931209e-08

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Performance plots


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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 369
Total TN 209645
Total FP 122
Total FP CONTRA 14
Total FP INCONS 78
Total FP COMP 30
Total FN 697
Total Scores
MCC 0.525
Average MCC ± 95% Confidence Intervals 0.518 ± 0.116
Sensitivity 0.346
Positive Predictive Value 0.800
Nr of predictions 28

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2L94_A 0.87 0.80 0.94 16 973 1 0 1 0 4
2WRQ_Y 0.57 0.59 0.56 10 2832 12 5 3 4 7
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3A2K_C 0.72 0.61 0.85 17 2906 3 0 3 0 11
3AMU_B 0.77 0.59 1.00 16 2987 1 0 0 1 11
3G4S_9 0.48 0.32 0.75 18 7357 8 1 5 2 39
3GX2_A 0.39 0.28 0.55 11 4351 10 0 9 1 29
3IVN_B 0.78 0.65 0.95 20 2325 1 1 0 0 11
3IZ4_A 0.00 0.00 0.00 0 70876 0 0 0 0 132
3IZF_C 0.73 0.63 0.85 34 6863 7 1 5 1 20
3JYV_7 0.81 0.66 1.00 21 2829 0 0 0 0 11
3JYX_3 0.56 0.56 0.58 15 6302 23 1 10 12 12
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3LA5_A 0.76 0.59 1.00 20 2465 0 0 0 0 14
3NPB_A 0.30 0.24 0.39 11 6993 18 1 16 1 35
3O58_2 0.76 0.76 0.76 29 7222 12 3 6 3 9
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.70 0.50 1.00 17 2194 0 0 0 0 17
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
4A1C_3 0.70 0.59 0.84 32 7102 7 0 6 1 22
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Performance of Vsfold5 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold5

Total Base Pair Counts
Total TP 370
Total TN 209336
Total FP 451
Total FP CONTRA 52
Total FP INCONS 348
Total FP COMP 51
Total FN 696
Total Scores
MCC 0.406
Average MCC ± 95% Confidence Intervals 0.458 ± 0.126
Sensitivity 0.347
Positive Predictive Value 0.481
Nr of predictions 28

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2. Individual counts for Vsfold5 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.90 0.82 1.00 9 397 0 0 0 0 2
2L94_A 0.95 0.90 1.00 18 972 0 0 0 0 2
2WRQ_Y 0.53 0.53 0.53 9 2833 12 5 3 4 8
2XKV_B -0.01 0.00 0.00 0 4528 32 12 20 0 20
2XQD_Y 0.86 0.74 1.00 20 2830 0 0 0 0 7
2XXA_G -0.01 0.00 0.00 0 5120 31 2 29 0 42
3A2K_C 0.84 0.71 1.00 20 2906 0 0 0 0 8
3AMU_B 0.67 0.59 0.76 16 2982 7 0 5 2 11
3G4S_9 0.08 0.07 0.11 4 7344 33 0 33 0 53
3GX2_A 0.51 0.40 0.67 16 4347 9 0 8 1 24
3IVN_B 0.76 0.58 1.00 18 2328 0 0 0 0 13
3IZ4_A 0.29 0.24 0.36 32 70787 62 8 49 5 100
3IZF_C 0.70 0.56 0.88 30 6869 4 0 4 0 24
3JYV_7 -0.01 0.00 0.00 0 2831 19 0 19 0 32
3JYX_3 0.17 0.15 0.20 4 6308 18 4 12 2 23
3JYX_4 0.31 0.30 0.31 10 12214 32 3 19 10 23
3LA5_A -0.01 0.00 0.00 0 2469 16 0 16 0 34
3NPB_A 0.57 0.46 0.72 21 6992 9 1 7 1 25
3O58_2 0.45 0.42 0.48 16 7227 19 3 14 2 22
3O58_3 0.39 0.37 0.41 13 12371 28 7 12 9 22
3PDR_A 0.57 0.44 0.74 32 12837 13 0 11 2 40
3RKF_A 0.75 0.65 0.88 22 2186 3 0 3 0 12
3SD1_A 0.11 0.10 0.15 4 3890 22 0 22 0 38
4A1C_3 0.26 0.22 0.32 12 7103 25 2 23 0 42
4A1C_2 0.24 0.24 0.24 8 11748 37 3 22 12 25
4AOB_A 0.18 0.14 0.25 6 4347 19 1 17 1 36
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.