CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of McQFold - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for McQFold & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric McQFold Murlet(seed)
MCC 0.647 > 0.539
Average MCC ± 95% Confidence Intervals 0.695 ± 0.107 > 0.545 ± 0.074
Sensitivity 0.570 > 0.337
Positive Predictive Value 0.740 < 0.868
Total TP 446 > 264
Total TN 104196 < 104495
Total FP 189 > 46
Total FP CONTRA 28 > 5
Total FP INCONS 129 > 35
Total FP COMP 32 > 6
Total FN 337 < 519
P-value 5.02343278931e-08

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Performance plots


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Performance of McQFold - scored higher in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 446
Total TN 104196
Total FP 189
Total FP CONTRA 28
Total FP INCONS 129
Total FP COMP 32
Total FN 337
Total Scores
MCC 0.647
Average MCC ± 95% Confidence Intervals 0.695 ± 0.107
Sensitivity 0.570
Positive Predictive Value 0.740
Nr of predictions 26

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.89 0.79 1.00 15 1113 1 0 0 1 4
2KUR_A 0.87 0.76 1.00 16 1112 0 0 0 0 5
2KUU_A 0.84 0.71 1.00 15 1113 1 0 0 1 6
2KUV_A 0.85 0.73 1.00 16 1112 0 0 0 0 6
2KUW_A 0.87 0.76 1.00 16 1112 0 0 0 0 5
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
2XKV_B 0.31 0.30 0.33 6 4542 25 1 11 13 14
2XXA_G 0.27 0.24 0.32 10 5120 21 0 21 0 32
3A3A_A 0.87 0.76 1.00 28 3627 0 0 0 0 9
3GX2_A 0.47 0.40 0.57 16 4343 13 1 11 1 24
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.20 0.21 0.19 7 12210 33 8 21 4 26
3LA5_A 0.78 0.62 1.00 21 2464 0 0 0 0 13
3NPB_A 0.81 0.67 0.97 31 6989 4 1 0 3 15
3O58_3 0.26 0.26 0.26 9 12368 26 10 16 0 26
3PDR_A 0.69 0.56 0.87 40 12834 9 0 6 3 32
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.71 0.60 0.86 25 3887 4 0 4 0 17
4A1C_2 0.15 0.15 0.15 5 11748 33 5 23 5 28
4AOB_A 0.42 0.33 0.54 14 4345 13 1 11 1 28
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 264
Total TN 104495
Total FP 46
Total FP CONTRA 5
Total FP INCONS 35
Total FP COMP 6
Total FN 519
Total Scores
MCC 0.539
Average MCC ± 95% Confidence Intervals 0.545 ± 0.074
Sensitivity 0.337
Positive Predictive Value 0.868
Nr of predictions 26

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.52 0.27 1.00 3 403 0 0 0 0 8
2KE6_A 0.66 0.53 0.83 10 1116 2 0 2 0 9
2KUR_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUU_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUV_A 0.85 0.73 1.00 16 1112 0 0 0 0 6
2KUW_A 0.84 0.76 0.94 16 1111 1 0 1 0 5
2L1F_A 0.82 0.75 0.90 18 2060 2 0 2 0 6
2L1F_B 0.80 0.72 0.90 18 2125 2 0 2 0 7
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
2XXA_G 0.38 0.14 1.00 6 5145 0 0 0 0 36
3A3A_A 0.57 0.32 1.00 12 3643 0 0 0 0 25
3GX2_A 0.59 0.35 1.00 14 4357 1 0 0 1 26
3IVN_B 0.53 0.39 0.75 12 2330 4 2 2 0 19
3JYX_4 0.23 0.09 0.60 3 12241 4 0 2 2 30
3LA5_A 0.58 0.41 0.82 14 2468 3 1 2 0 20
3NPB_A 0.49 0.28 0.87 13 7006 2 1 1 0 33
3O58_3 0.45 0.20 1.00 7 12396 0 0 0 0 28
3PDR_A 0.44 0.19 1.00 14 12866 0 0 0 0 58
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.