CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RNAwolf [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RNAwolf
MCC 0.538 > 0.466
Average MCC ± 95% Confidence Intervals 0.478 ± 0.538 < 0.482 ± 0.318
Sensitivity 0.420 > 0.413
Positive Predictive Value 0.699 > 0.538
Total TP 58 > 57
Total TN 11955 > 11932
Total FP 26 < 50
Total FP CONTRA 2 > 1
Total FP INCONS 23 < 48
Total FP COMP 1 = 1
Total FN 80 < 81
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RNAwolf).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 11955
Total FP 26
Total FP CONTRA 2
Total FP INCONS 23
Total FP COMP 1
Total FN 80
Total Scores
MCC 0.538
Average MCC ± 95% Confidence Intervals 0.478 ± 0.538
Sensitivity 0.420
Positive Predictive Value 0.699
Nr of predictions 4

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 57
Total TN 11932
Total FP 50
Total FP CONTRA 1
Total FP INCONS 48
Total FP COMP 1
Total FN 81
Total Scores
MCC 0.466
Average MCC ± 95% Confidence Intervals 0.482 ± 0.318
Sensitivity 0.413
Positive Predictive Value 0.538
Nr of predictions 4

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.50 0.56 10 1522 8 0 8 0 10
3RKF_A 0.72 0.62 0.84 21 2186 4 0 4 0 13
3SD1_A 0.46 0.43 0.50 18 3880 18 0 18 0 24
4AOB_A 0.23 0.19 0.30 8 4344 20 1 18 1 34

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.