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Table of contents:
- Overview
- Performance Plots
- Performance of Murlet(20) - scored higher in this pairwise comparison
- Performance of McQFold - scored lower in this pairwise comparison
- Compile and download dataset for Murlet(20) & McQFold [.zip] - may take several seconds...
Overview
| Metric | Murlet(20) | McQFold | |
|---|---|---|---|
| MCC | 0.582 | > | 0.524 |
| Average MCC ± 95% Confidence Intervals | 0.586 ± 0.064 | > | 0.572 ± 0.113 |
| Sensitivity | 0.423 | < | 0.454 |
| Positive Predictive Value | 0.804 | > | 0.609 |
| Total TP | 451 | < | 484 |
| Total TN | 209545 | > | 209311 |
| Total FP | 141 | < | 353 |
| Total FP CONTRA | 14 | < | 50 |
| Total FP INCONS | 96 | < | 261 |
| Total FP COMP | 31 | < | 42 |
| Total FN | 615 | > | 582 |
| P-value | 5.19332990918e-08 | ||
Performance plots
Performance of Murlet(20) - scored higher in this pairwise comparison
1. Total counts & total scores for Murlet(20)
| Total Base Pair Counts | |
|---|---|
| Total TP | 451 |
| Total TN | 209545 |
| Total FP | 141 |
| Total FP CONTRA | 14 |
| Total FP INCONS | 96 |
| Total FP COMP | 31 |
| Total FN | 615 |
| Total Scores | |
|---|---|
| MCC | 0.582 |
| Average MCC ± 95% Confidence Intervals | 0.586 ± 0.064 |
| Sensitivity | 0.423 |
| Positive Predictive Value | 0.804 |
| Nr of predictions | 28 |
2. Individual counts for Murlet(20) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.67 | 0.45 | 1.00 | 5 | 401 | 0 | 0 | 0 | 0 | 6 | |
| 2L94_A | 0.53 | 0.50 | 0.59 | 10 | 973 | 7 | 0 | 7 | 0 | 10 | |
| 2WRQ_Y | 0.41 | 0.41 | 0.41 | 7 | 2833 | 12 | 6 | 4 | 2 | 10 | |
| 2XKV_B | 0.45 | 0.20 | 1.00 | 4 | 4556 | 3 | 0 | 0 | 3 | 16 | |
| 2XQD_Y | 0.80 | 0.70 | 0.90 | 19 | 2829 | 2 | 0 | 2 | 0 | 8 | |
| 2XXA_G | 0.41 | 0.17 | 1.00 | 7 | 5144 | 0 | 0 | 0 | 0 | 35 | |
| 3A2K_C | 0.78 | 0.68 | 0.90 | 19 | 2905 | 2 | 0 | 2 | 0 | 9 | |
| 3AMU_B | 0.77 | 0.67 | 0.90 | 18 | 2983 | 3 | 0 | 2 | 1 | 9 | |
| 3G4S_9 | 0.58 | 0.39 | 0.88 | 22 | 7356 | 3 | 1 | 2 | 0 | 35 | |
| 3GX2_A | 0.61 | 0.38 | 1.00 | 15 | 4356 | 1 | 0 | 0 | 1 | 25 | |
| 3IVN_B | 0.69 | 0.48 | 1.00 | 15 | 2331 | 0 | 0 | 0 | 0 | 16 | |
| 3IZ4_A | 0.40 | 0.24 | 0.65 | 32 | 70827 | 21 | 1 | 16 | 4 | 100 | |
| 3IZF_C | 0.71 | 0.56 | 0.91 | 30 | 6870 | 4 | 0 | 3 | 1 | 24 | |
| 3JYV_7 | 0.67 | 0.53 | 0.85 | 17 | 2830 | 3 | 0 | 3 | 0 | 15 | |
| 3JYX_3 | 0.60 | 0.52 | 0.70 | 14 | 6308 | 11 | 0 | 6 | 5 | 13 | |
| 3JYX_4 | 0.36 | 0.27 | 0.47 | 9 | 12227 | 15 | 0 | 10 | 5 | 24 | |
| 3LA5_A | 0.68 | 0.47 | 1.00 | 16 | 2469 | 0 | 0 | 0 | 0 | 18 | |
| 3NPB_A | 0.55 | 0.35 | 0.89 | 16 | 7003 | 2 | 1 | 1 | 0 | 30 | |
| 3O58_2 | 0.89 | 0.82 | 0.97 | 31 | 7228 | 2 | 0 | 1 | 1 | 7 | |
| 3O58_3 | 0.33 | 0.23 | 0.47 | 8 | 12386 | 12 | 2 | 7 | 3 | 27 | |
| 3PDR_A | 0.70 | 0.53 | 0.93 | 38 | 12839 | 3 | 0 | 3 | 0 | 34 | |
| 3RKF_A | 0.68 | 0.47 | 1.00 | 16 | 2195 | 0 | 0 | 0 | 0 | 18 | |
| 3SD1_A | 0.68 | 0.57 | 0.83 | 24 | 3887 | 5 | 1 | 4 | 0 | 18 | |
| 4A1C_3 | 0.59 | 0.41 | 0.85 | 22 | 7114 | 4 | 0 | 4 | 0 | 32 | |
| 4A1C_2 | 0.17 | 0.15 | 0.20 | 5 | 11756 | 24 | 2 | 18 | 4 | 28 | |
| 4AOB_A | 0.72 | 0.55 | 0.96 | 23 | 4347 | 2 | 0 | 1 | 1 | 19 | |
| 4ENB_A | 0.46 | 0.21 | 1.00 | 4 | 1271 | 0 | 0 | 0 | 0 | 15 | |
| 4ENC_A | 0.51 | 0.26 | 1.00 | 5 | 1321 | 0 | 0 | 0 | 0 | 14 |
Performance of McQFold - scored lower in this pairwise comparison
1. Total counts & total scores for McQFold
| Total Base Pair Counts | |
|---|---|
| Total TP | 484 |
| Total TN | 209311 |
| Total FP | 353 |
| Total FP CONTRA | 50 |
| Total FP INCONS | 261 |
| Total FP COMP | 42 |
| Total FN | 582 |
| Total Scores | |
|---|---|
| MCC | 0.524 |
| Average MCC ± 95% Confidence Intervals | 0.572 ± 0.113 |
| Sensitivity | 0.454 |
| Positive Predictive Value | 0.609 |
| Nr of predictions | 28 |
2. Individual counts for McQFold [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2WRQ_Y | 0.57 | 0.59 | 0.56 | 10 | 2832 | 13 | 5 | 3 | 5 | 7 | |
| 2XKV_B | 0.31 | 0.30 | 0.33 | 6 | 4542 | 25 | 1 | 11 | 13 | 14 | |
| 2XQD_Y | 0.88 | 0.78 | 1.00 | 21 | 2829 | 0 | 0 | 0 | 0 | 6 | |
| 2XXA_G | 0.27 | 0.24 | 0.32 | 10 | 5120 | 21 | 0 | 21 | 0 | 32 | |
| 3A2K_C | 0.86 | 0.75 | 1.00 | 21 | 2905 | 0 | 0 | 0 | 0 | 7 | |
| 3AMU_B | 0.75 | 0.59 | 0.94 | 16 | 2986 | 3 | 0 | 1 | 2 | 11 | |
| 3G4S_9 | 0.27 | 0.21 | 0.36 | 12 | 7348 | 21 | 1 | 20 | 0 | 45 | |
| 3GX2_A | 0.47 | 0.40 | 0.57 | 16 | 4343 | 13 | 1 | 11 | 1 | 24 | |
| 3IVN_B | 0.78 | 0.61 | 1.00 | 19 | 2327 | 0 | 0 | 0 | 0 | 12 | |
| 3IZ4_A | 0.42 | 0.36 | 0.49 | 47 | 70780 | 53 | 6 | 43 | 4 | 85 | |
| 3IZF_C | 0.68 | 0.56 | 0.83 | 30 | 6867 | 6 | 0 | 6 | 0 | 24 | |
| 3JYV_7 | -0.01 | 0.00 | 0.00 | 0 | 2830 | 20 | 0 | 20 | 0 | 32 | |
| 3JYX_3 | 0.21 | 0.22 | 0.20 | 6 | 6298 | 24 | 9 | 15 | 0 | 21 | |
| 3JYX_4 | 0.20 | 0.21 | 0.19 | 7 | 12210 | 33 | 8 | 21 | 4 | 26 | |
| 3LA5_A | 0.78 | 0.62 | 1.00 | 21 | 2464 | 0 | 0 | 0 | 0 | 13 | |
| 3NPB_A | 0.81 | 0.67 | 0.97 | 31 | 6989 | 4 | 1 | 0 | 3 | 15 | |
| 3O58_2 | 0.83 | 0.71 | 0.96 | 27 | 7232 | 2 | 0 | 1 | 1 | 11 | |
| 3O58_3 | 0.26 | 0.26 | 0.26 | 9 | 12368 | 26 | 10 | 16 | 0 | 26 | |
| 3PDR_A | 0.69 | 0.56 | 0.87 | 40 | 12834 | 9 | 0 | 6 | 3 | 32 | |
| 3RKF_A | 0.76 | 0.59 | 1.00 | 20 | 2191 | 0 | 0 | 0 | 0 | 14 | |
| 3SD1_A | 0.71 | 0.60 | 0.86 | 25 | 3887 | 4 | 0 | 4 | 0 | 17 | |
| 4A1C_3 | 0.25 | 0.22 | 0.29 | 12 | 7099 | 29 | 1 | 28 | 0 | 42 | |
| 4A1C_2 | 0.15 | 0.15 | 0.15 | 5 | 11748 | 33 | 5 | 23 | 5 | 28 | |
| 4AOB_A | 0.42 | 0.33 | 0.54 | 14 | 4345 | 13 | 1 | 11 | 1 | 28 | |
| 4ENB_A | 0.89 | 0.79 | 1.00 | 15 | 1260 | 0 | 0 | 0 | 0 | 4 | |
| 4ENC_A | 0.86 | 0.79 | 0.94 | 15 | 1310 | 1 | 1 | 0 | 0 | 4 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.