CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of Vsfold5 - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & Vsfold5 [.zip] - may take several seconds...


Overview

Metric Murlet(seed) Vsfold5
MCC 0.539 > 0.520
Average MCC ± 95% Confidence Intervals 0.545 ± 0.074 < 0.575 ± 0.145
Sensitivity 0.337 < 0.455
Positive Predictive Value 0.868 > 0.602
Total TP 264 < 356
Total TN 104495 > 104208
Total FP 46 < 273
Total FP CONTRA 5 < 30
Total FP INCONS 35 < 205
Total FP COMP 6 < 38
Total FN 519 > 427
P-value 5.36978958876e-05

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Performance plots


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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 264
Total TN 104495
Total FP 46
Total FP CONTRA 5
Total FP INCONS 35
Total FP COMP 6
Total FN 519
Total Scores
MCC 0.539
Average MCC ± 95% Confidence Intervals 0.545 ± 0.074
Sensitivity 0.337
Positive Predictive Value 0.868
Nr of predictions 26

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.52 0.27 1.00 3 403 0 0 0 0 8
2KE6_A 0.66 0.53 0.83 10 1116 2 0 2 0 9
2KUR_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUU_A 0.63 0.48 0.83 10 1116 2 0 2 0 11
2KUV_A 0.85 0.73 1.00 16 1112 0 0 0 0 6
2KUW_A 0.84 0.76 0.94 16 1111 1 0 1 0 5
2L1F_A 0.82 0.75 0.90 18 2060 2 0 2 0 6
2L1F_B 0.80 0.72 0.90 18 2125 2 0 2 0 7
2L94_A 0.59 0.40 0.89 8 981 1 0 1 0 12
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
2XXA_G 0.38 0.14 1.00 6 5145 0 0 0 0 36
3A3A_A 0.57 0.32 1.00 12 3643 0 0 0 0 25
3GX2_A 0.59 0.35 1.00 14 4357 1 0 0 1 26
3IVN_B 0.53 0.39 0.75 12 2330 4 2 2 0 19
3JYX_4 0.23 0.09 0.60 3 12241 4 0 2 2 30
3LA5_A 0.58 0.41 0.82 14 2468 3 1 2 0 20
3NPB_A 0.49 0.28 0.87 13 7006 2 1 1 0 33
3O58_3 0.45 0.20 1.00 7 12396 0 0 0 0 28
3PDR_A 0.44 0.19 1.00 14 12866 0 0 0 0 58
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of Vsfold5 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold5

Total Base Pair Counts
Total TP 356
Total TN 104208
Total FP 273
Total FP CONTRA 30
Total FP INCONS 205
Total FP COMP 38
Total FN 427
Total Scores
MCC 0.520
Average MCC ± 95% Confidence Intervals 0.575 ± 0.145
Sensitivity 0.455
Positive Predictive Value 0.602
Nr of predictions 26

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2. Individual counts for Vsfold5 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.90 0.82 1.00 9 397 0 0 0 0 2
2KE6_A 0.97 0.95 1.00 18 1110 1 0 0 1 1
2KUR_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2KUU_A 0.92 0.86 1.00 18 1110 1 0 0 1 3
2KUV_A 0.93 0.86 1.00 19 1109 0 0 0 0 3
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_A 0.69 0.58 0.82 14 2063 3 0 3 0 10
2L1F_B 0.70 0.60 0.83 15 2127 3 0 3 0 10
2L94_A 0.95 0.90 1.00 18 972 0 0 0 0 2
2LC8_A -0.01 0.00 0.00 0 1527 13 0 13 0 20
2XKV_B -0.01 0.00 0.00 0 4528 32 12 20 0 20
2XXA_G -0.01 0.00 0.00 0 5120 31 2 29 0 42
3A3A_A 0.85 0.73 1.00 27 3628 0 0 0 0 10
3GX2_A 0.51 0.40 0.67 16 4347 9 0 8 1 24
3IVN_B 0.76 0.58 1.00 18 2328 0 0 0 0 13
3JYX_4 0.31 0.30 0.31 10 12214 32 3 19 10 23
3LA5_A -0.01 0.00 0.00 0 2469 16 0 16 0 34
3NPB_A 0.57 0.46 0.72 21 6992 9 1 7 1 25
3O58_3 0.39 0.37 0.41 13 12371 28 7 12 9 22
3PDR_A 0.57 0.44 0.74 32 12837 13 0 11 2 40
3RKF_A 0.75 0.65 0.88 22 2186 3 0 3 0 12
3SD1_A 0.11 0.10 0.15 4 3890 22 0 22 0 38
4A1C_2 0.24 0.24 0.24 8 11748 37 3 22 12 25
4AOB_A 0.18 0.14 0.25 6 4347 19 1 17 1 36
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.