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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of CentroidAlifold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & CentroidAlifold(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) CentroidAlifold(seed)
MCC 0.625 > 0.613
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 < 0.611 ± 0.138
Sensitivity 0.497 > 0.383
Positive Predictive Value 0.790 < 0.985
Total TP 83 > 64
Total TN 25788 < 25828
Total FP 33 > 4
Total FP CONTRA 0 = 0
Total FP INCONS 22 > 1
Total FP COMP 11 > 3
Total FN 84 < 103
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and CentroidAlifold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidAlifold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and CentroidAlifold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and CentroidAlifold(seed)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of CentroidAlifold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidAlifold(seed)

Total Base Pair Counts
Total TP 64
Total TN 25828
Total FP 4
Total FP CONTRA 0
Total FP INCONS 1
Total FP COMP 3
Total FN 103
Total Scores
MCC 0.613
Average MCC ± 95% Confidence Intervals 0.611 ± 0.138
Sensitivity 0.383
Positive Predictive Value 0.985
Nr of predictions 5

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2. Individual counts for CentroidAlifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.54 0.30 1.00 16 7124 0 0 0 0 38
4A1C_2 0.46 0.24 0.89 8 11772 3 0 1 2 25
4AOB_A 0.75 0.57 1.00 24 4347 1 0 0 1 18
4ENB_A 0.65 0.42 1.00 8 1267 0 0 0 0 11
4ENC_A 0.65 0.42 1.00 8 1318 0 0 0 0 11

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.