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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of MCFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & MCFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) MCFold
MCC 0.586 > 0.444
Average MCC ± 95% Confidence Intervals 0.541 ± 0.412 > 0.425 ± 0.422
Sensitivity 0.464 < 0.472
Positive Predictive Value 0.744 > 0.424
Total TP 58 < 59
Total TN 21444 > 21383
Total FP 30 < 98
Total FP CONTRA 0 < 15
Total FP INCONS 20 < 65
Total FP COMP 10 < 18
Total FN 67 > 66
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and MCFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and MCFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and MCFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and MCFold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 58
Total TN 21444
Total FP 30
Total FP CONTRA 0
Total FP INCONS 20
Total FP COMP 10
Total FN 67
Total Scores
MCC 0.586
Average MCC ± 95% Confidence Intervals 0.541 ± 0.412
Sensitivity 0.464
Positive Predictive Value 0.744
Nr of predictions 4

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of MCFold - scored lower in this pairwise comparison

1. Total counts & total scores for MCFold

Total Base Pair Counts
Total TP 59
Total TN 21383
Total FP 98
Total FP CONTRA 15
Total FP INCONS 65
Total FP COMP 18
Total FN 66
Total Scores
MCC 0.444
Average MCC ± 95% Confidence Intervals 0.425 ± 0.422
Sensitivity 0.472
Positive Predictive Value 0.424
Nr of predictions 4

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2. Individual counts for MCFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.68 0.67 0.71 36 7089 17 1 14 2 18
4A1C_2 0.13 0.15 0.11 5 11735 56 10 31 15 28
4ENB_A 0.61 0.63 0.60 12 1255 8 2 6 0 7
4ENC_A 0.28 0.32 0.27 6 1304 17 2 14 1 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.