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Table of contents:
- Overview
- Performance Plots
- Performance of Pknots - scored higher in this pairwise comparison
- Performance of RNASampler(seed) - scored lower in this pairwise comparison
- Compile and download dataset for Pknots & RNASampler(seed) [.zip] - may take several seconds...
Overview
| Metric | Pknots | RNASampler(seed) | |
|---|---|---|---|
| MCC | 0.701 | > | 0.673 |
| Average MCC ± 95% Confidence Intervals | 0.771 ± 0.140 | > | 0.690 ± 0.136 |
| Sensitivity | 0.668 | > | 0.535 |
| Positive Predictive Value | 0.739 | < | 0.851 |
| Total TP | 300 | > | 240 |
| Total TN | 60953 | < | 61077 |
| Total FP | 128 | > | 59 |
| Total FP CONTRA | 28 | > | 4 |
| Total FP INCONS | 78 | > | 38 |
| Total FP COMP | 22 | > | 17 |
| Total FN | 149 | < | 209 |
| P-value | 2.87234834547e-08 | ||
Performance plots
Performance of Pknots - scored higher in this pairwise comparison
1. Total counts & total scores for Pknots
| Total Base Pair Counts | |
|---|---|
| Total TP | 300 |
| Total TN | 60953 |
| Total FP | 128 |
| Total FP CONTRA | 28 |
| Total FP INCONS | 78 |
| Total FP COMP | 22 |
| Total FN | 149 |
| Total Scores | |
|---|---|
| MCC | 0.701 |
| Average MCC ± 95% Confidence Intervals | 0.771 ± 0.140 |
| Sensitivity | 0.668 |
| Positive Predictive Value | 0.739 |
| Nr of predictions | 17 |
2. Individual counts for Pknots [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2KE6_A | 0.97 | 0.95 | 1.00 | 18 | 1110 | 1 | 0 | 0 | 1 | 1 | |
| 2KUR_A | 0.95 | 0.90 | 1.00 | 19 | 1109 | 0 | 0 | 0 | 0 | 2 | |
| 2KUU_A | 0.92 | 0.86 | 1.00 | 18 | 1110 | 1 | 0 | 0 | 1 | 3 | |
| 2KUV_A | 0.93 | 0.86 | 1.00 | 19 | 1109 | 0 | 0 | 0 | 0 | 3 | |
| 2KUW_A | 0.95 | 0.90 | 1.00 | 19 | 1109 | 0 | 0 | 0 | 0 | 2 | |
| 2L1F_A | 0.98 | 0.96 | 1.00 | 23 | 2057 | 0 | 0 | 0 | 0 | 1 | |
| 2L1F_B | 0.98 | 0.96 | 1.00 | 24 | 2121 | 0 | 0 | 0 | 0 | 1 | |
| 2L94_A | 0.92 | 0.90 | 0.95 | 18 | 971 | 1 | 0 | 1 | 0 | 2 | |
| 2LC8_A | 0.79 | 0.75 | 0.83 | 15 | 1522 | 3 | 1 | 2 | 0 | 5 | |
| 3A3A_A | 0.87 | 0.76 | 1.00 | 28 | 3627 | 0 | 0 | 0 | 0 | 9 | |
| 3IVN_B | 0.78 | 0.65 | 0.95 | 20 | 2325 | 1 | 0 | 1 | 0 | 11 | |
| 3JYX_4 | 0.18 | 0.21 | 0.16 | 7 | 12203 | 41 | 13 | 23 | 5 | 26 | |
| 3O58_3 | 0.27 | 0.31 | 0.24 | 11 | 12357 | 38 | 11 | 24 | 3 | 24 | |
| 3RKF_A | 0.77 | 0.62 | 0.95 | 21 | 2189 | 1 | 0 | 1 | 0 | 13 | |
| 3SD1_A | 0.65 | 0.52 | 0.81 | 22 | 3889 | 5 | 0 | 5 | 0 | 20 | |
| 4A1C_2 | 0.24 | 0.24 | 0.25 | 8 | 11749 | 36 | 3 | 21 | 12 | 25 |
Performance of RNASampler(seed) - scored lower in this pairwise comparison
1. Total counts & total scores for RNASampler(seed)
| Total Base Pair Counts | |
|---|---|
| Total TP | 240 |
| Total TN | 61077 |
| Total FP | 59 |
| Total FP CONTRA | 4 |
| Total FP INCONS | 38 |
| Total FP COMP | 17 |
| Total FN | 209 |
| Total Scores | |
|---|---|
| MCC | 0.673 |
| Average MCC ± 95% Confidence Intervals | 0.690 ± 0.136 |
| Sensitivity | 0.535 |
| Positive Predictive Value | 0.851 |
| Nr of predictions | 17 |
2. Individual counts for RNASampler(seed) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2KE6_A | 0.92 | 0.84 | 1.00 | 16 | 1112 | 1 | 0 | 0 | 1 | 3 | |
| 2KUR_A | 0.90 | 0.81 | 1.00 | 17 | 1111 | 0 | 0 | 0 | 0 | 4 | |
| 2KUU_A | 0.87 | 0.76 | 1.00 | 16 | 1112 | 1 | 0 | 0 | 1 | 5 | |
| 2KUV_A | 0.88 | 0.77 | 1.00 | 17 | 1111 | 0 | 0 | 0 | 0 | 5 | |
| 2KUW_A | 0.90 | 0.81 | 1.00 | 17 | 1111 | 0 | 0 | 0 | 0 | 4 | |
| 2L1F_A | 0.81 | 0.67 | 1.00 | 16 | 2064 | 0 | 0 | 0 | 0 | 8 | |
| 2L1F_B | 0.82 | 0.68 | 1.00 | 17 | 2128 | 0 | 0 | 0 | 0 | 8 | |
| 2L94_A | 0.71 | 0.55 | 0.92 | 11 | 978 | 1 | 0 | 1 | 0 | 9 | |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1530 | 10 | 0 | 10 | 0 | 20 | |
| 3A3A_A | 0.70 | 0.49 | 1.00 | 18 | 3637 | 0 | 0 | 0 | 0 | 19 | |
| 3IVN_B | 0.78 | 0.61 | 1.00 | 19 | 2327 | 0 | 0 | 0 | 0 | 12 | |
| 3JYX_4 | 0.39 | 0.30 | 0.50 | 10 | 12226 | 13 | 2 | 8 | 3 | 23 | |
| 3O58_3 | 0.45 | 0.34 | 0.60 | 12 | 12383 | 12 | 2 | 6 | 4 | 23 | |
| 3RKF_A | 0.76 | 0.59 | 1.00 | 20 | 2191 | 0 | 0 | 0 | 0 | 14 | |
| 3SD1_A | 0.60 | 0.38 | 0.94 | 16 | 3899 | 1 | 0 | 1 | 0 | 26 | |
| 4A1C_2 | 0.31 | 0.24 | 0.40 | 8 | 11761 | 20 | 0 | 12 | 8 | 25 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.