CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PknotsRG - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for PknotsRG & CRWrnafold [.zip] - may take several seconds...


Overview

Metric PknotsRG CRWrnafold
MCC 0.621 > 0.585
Average MCC ± 95% Confidence Intervals 0.678 ± 0.114 > 0.639 ± 0.123
Sensitivity 0.563 > 0.522
Positive Predictive Value 0.692 > 0.663
Total TP 370 > 343
Total TN 69806 < 69824
Total FP 185 < 196
Total FP CONTRA 23 < 24
Total FP INCONS 142 < 150
Total FP COMP 20 < 22
Total FN 287 < 314
P-value 3.85233844192e-08

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Performance plots


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Performance of PknotsRG - scored higher in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 370
Total TN 69806
Total FP 185
Total FP CONTRA 23
Total FP INCONS 142
Total FP COMP 20
Total FN 287
Total Scores
MCC 0.621
Average MCC ± 95% Confidence Intervals 0.678 ± 0.114
Sensitivity 0.563
Positive Predictive Value 0.692
Nr of predictions 32

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LBS_A - 1.00 1.00 1.00 14 482 0 0 0 0 0
2LC8_A 0.63 0.55 0.73 11 1525 4 1 3 0 9
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LDT_A - 0.85 0.73 1.00 11 454 0 0 0 0 4
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.73 0.69 0.77 27 6070 8 2 6 0 12
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2YIE_Z - -0.01 0.00 0.00 0 1525 15 3 12 0 12
2YIE_X - 0.30 0.33 0.29 4 1364 10 2 8 0 8
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3J0L_7 - 0.28 0.29 0.29 5 1208 12 0 12 0 12
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_2 - 0.24 0.24 0.24 8 6183 27 2 23 2 25
3J0L_h - 0.75 0.60 0.93 26 6077 4 0 2 2 17
3J0L_a - 0.23 0.19 0.30 3 1118 7 1 6 0 13
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_1 - 0.76 0.63 0.92 12 1212 2 0 1 1 7
3J16_L 0.75 0.57 1.00 17 2758 0 0 0 0 13
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 1 0 0 1 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
4A1C_3 0.70 0.59 0.82 32 7101 7 1 6 0 22
4A1C_2 0.14 0.15 0.13 5 11742 43 5 29 9 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 343
Total TN 69824
Total FP 196
Total FP CONTRA 24
Total FP INCONS 150
Total FP COMP 22
Total FN 314
Total Scores
MCC 0.585
Average MCC ± 95% Confidence Intervals 0.639 ± 0.123
Sensitivity 0.522
Positive Predictive Value 0.663
Nr of predictions 32

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LBS_A - 1.00 1.00 1.00 14 482 0 0 0 0 0
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
2LDL_A - 0.85 0.73 1.00 8 343 1 0 0 1 3
2LDT_A - 0.85 0.73 1.00 11 454 0 0 0 0 4
2LHP_A - 0.93 0.88 1.00 14 652 0 0 0 0 2
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.52 0.44 0.63 17 6078 12 2 8 2 22
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2YIE_Z - -0.01 0.00 0.00 0 1525 15 3 12 0 12
2YIE_X - 0.36 0.33 0.40 4 1368 9 2 4 3 8
3AMU_B 0.67 0.59 0.76 16 2982 7 0 5 2 11
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_2 - 0.25 0.24 0.28 8 6187 23 2 19 2 25
3J0L_h - 0.81 0.65 1.00 28 6077 0 0 0 0 15
3J0L_a - 0.39 0.31 0.50 5 1118 5 1 4 0 11
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_1 - 0.76 0.63 0.92 12 1212 3 0 1 2 7
3J16_L 0.84 0.70 1.00 21 2754 0 0 0 0 9
3SD1_A 0.52 0.45 0.61 19 3885 12 2 10 0 23
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 0 0 0 0 1
3TS0_U - 1.00 1.00 1.00 6 247 0 0 0 0 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
4A1C_3 0.70 0.59 0.84 32 7102 6 0 6 0 22
4A1C_2 0.13 0.15 0.13 5 11741 44 4 31 9 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.59 0.48 0.74 20 4344 8 2 5 1 22
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.70 0.58 0.85 11 1313 2 1 1 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.