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Table of contents:
- Overview
- Performance Plots
- Performance of ProbKnot - scored higher in this pairwise comparison
- Performance of Murlet(20) - scored lower in this pairwise comparison
- Compile and download dataset for ProbKnot & Murlet(20) [.zip] - may take several seconds...
Overview
| Metric | ProbKnot | Murlet(20) | |
|---|---|---|---|
| MCC | 0.586 | > | 0.575 |
| Average MCC ± 95% Confidence Intervals | 0.605 ± 0.109 | > | 0.575 ± 0.092 |
| Sensitivity | 0.529 | > | 0.413 |
| Positive Predictive Value | 0.653 | < | 0.804 |
| Total TP | 400 | > | 312 |
| Total TN | 165304 | < | 165529 |
| Total FP | 267 | > | 94 |
| Total FP CONTRA | 31 | > | 7 |
| Total FP INCONS | 182 | > | 69 |
| Total FP COMP | 54 | > | 18 |
| Total FN | 356 | < | 444 |
| P-value | 5.00648371734e-07 | ||
Performance plots
Performance of ProbKnot - scored higher in this pairwise comparison
1. Total counts & total scores for ProbKnot
| Total Base Pair Counts | |
|---|---|
| Total TP | 400 |
| Total TN | 165304 |
| Total FP | 267 |
| Total FP CONTRA | 31 |
| Total FP INCONS | 182 |
| Total FP COMP | 54 |
| Total FN | 356 |
| Total Scores | |
|---|---|
| MCC | 0.586 |
| Average MCC ± 95% Confidence Intervals | 0.605 ± 0.109 |
| Sensitivity | 0.529 |
| Positive Predictive Value | 0.653 |
| Nr of predictions | 18 |
2. Individual counts for ProbKnot [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2XKV_B | 0.51 | 0.50 | 0.53 | 10 | 4541 | 24 | 0 | 9 | 15 | 10 | |
| 2XQD_Y | 0.90 | 0.81 | 1.00 | 22 | 2828 | 1 | 0 | 0 | 1 | 5 | |
| 2XXA_G | 0.26 | 0.24 | 0.29 | 10 | 5116 | 25 | 1 | 24 | 0 | 32 | |
| 3AMU_B | 0.65 | 0.59 | 0.73 | 16 | 2981 | 8 | 0 | 6 | 2 | 11 | |
| 3IZ4_A | 0.52 | 0.46 | 0.60 | 61 | 70774 | 46 | 6 | 35 | 5 | 71 | |
| 3IZF_C | 0.72 | 0.61 | 0.85 | 33 | 6864 | 6 | 0 | 6 | 0 | 21 | |
| 3NPB_A | 0.72 | 0.61 | 0.85 | 28 | 6988 | 8 | 1 | 4 | 3 | 18 | |
| 3O58_3 | 0.31 | 0.34 | 0.29 | 12 | 12362 | 41 | 4 | 25 | 12 | 23 | |
| 3O58_2 | 0.76 | 0.76 | 0.76 | 29 | 7222 | 10 | 3 | 6 | 1 | 9 | |
| 3PDR_A | 0.74 | 0.64 | 0.85 | 46 | 12826 | 10 | 1 | 7 | 2 | 26 | |
| 3RKF_A | 0.73 | 0.59 | 0.91 | 20 | 2189 | 2 | 1 | 1 | 0 | 14 | |
| 3SD1_A | 0.55 | 0.48 | 0.65 | 20 | 3885 | 11 | 2 | 9 | 0 | 22 | |
| 4A1C_3 | 0.73 | 0.61 | 0.87 | 33 | 7102 | 6 | 1 | 4 | 1 | 21 | |
| 4A1C_2 | 0.13 | 0.15 | 0.12 | 5 | 11738 | 49 | 7 | 31 | 11 | 28 | |
| 4AOB_A | 0.50 | 0.40 | 0.63 | 17 | 4344 | 11 | 2 | 8 | 1 | 25 | |
| 4ENB_A | 0.73 | 0.58 | 0.92 | 11 | 1263 | 1 | 1 | 0 | 0 | 8 | |
| 4ENC_A | 0.45 | 0.42 | 0.50 | 8 | 1310 | 8 | 1 | 7 | 0 | 11 |
Performance of Murlet(20) - scored lower in this pairwise comparison
1. Total counts & total scores for Murlet(20)
| Total Base Pair Counts | |
|---|---|
| Total TP | 312 |
| Total TN | 165529 |
| Total FP | 94 |
| Total FP CONTRA | 7 |
| Total FP INCONS | 69 |
| Total FP COMP | 18 |
| Total FN | 444 |
| Total Scores | |
|---|---|
| MCC | 0.575 |
| Average MCC ± 95% Confidence Intervals | 0.575 ± 0.092 |
| Sensitivity | 0.413 |
| Positive Predictive Value | 0.804 |
| Nr of predictions | 18 |
2. Individual counts for Murlet(20) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2L94_A | 0.53 | 0.50 | 0.59 | 10 | 973 | 7 | 0 | 7 | 0 | 10 | |
| 2XKV_B | 0.45 | 0.20 | 1.00 | 4 | 4556 | 3 | 0 | 0 | 3 | 16 | |
| 2XQD_Y | 0.80 | 0.70 | 0.90 | 19 | 2829 | 2 | 0 | 2 | 0 | 8 | |
| 2XXA_G | 0.41 | 0.17 | 1.00 | 7 | 5144 | 0 | 0 | 0 | 0 | 35 | |
| 3AMU_B | 0.77 | 0.67 | 0.90 | 18 | 2983 | 3 | 0 | 2 | 1 | 9 | |
| 3IZ4_A | 0.40 | 0.24 | 0.65 | 32 | 70827 | 21 | 1 | 16 | 4 | 100 | |
| 3IZF_C | 0.71 | 0.56 | 0.91 | 30 | 6870 | 4 | 0 | 3 | 1 | 24 | |
| 3NPB_A | 0.55 | 0.35 | 0.89 | 16 | 7003 | 2 | 1 | 1 | 0 | 30 | |
| 3O58_3 | 0.33 | 0.23 | 0.47 | 8 | 12386 | 12 | 2 | 7 | 3 | 27 | |
| 3O58_2 | 0.89 | 0.82 | 0.97 | 31 | 7228 | 2 | 0 | 1 | 1 | 7 | |
| 3PDR_A | 0.70 | 0.53 | 0.93 | 38 | 12839 | 3 | 0 | 3 | 0 | 34 | |
| 3RKF_A | 0.68 | 0.47 | 1.00 | 16 | 2195 | 0 | 0 | 0 | 0 | 18 | |
| 3SD1_A | 0.68 | 0.57 | 0.83 | 24 | 3887 | 5 | 1 | 4 | 0 | 18 | |
| 4A1C_3 | 0.59 | 0.41 | 0.85 | 22 | 7114 | 4 | 0 | 4 | 0 | 32 | |
| 4A1C_2 | 0.17 | 0.15 | 0.20 | 5 | 11756 | 24 | 2 | 18 | 4 | 28 | |
| 4AOB_A | 0.72 | 0.55 | 0.96 | 23 | 4347 | 2 | 0 | 1 | 1 | 19 | |
| 4ENB_A | 0.46 | 0.21 | 1.00 | 4 | 1271 | 0 | 0 | 0 | 0 | 15 | |
| 4ENC_A | 0.51 | 0.26 | 1.00 | 5 | 1321 | 0 | 0 | 0 | 0 | 14 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.