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Table of contents:
- Overview
- Performance Plots
- Performance of RNASLOpt - scored higher in this pairwise comparison
- Performance of Pknots - scored lower in this pairwise comparison
- Compile and download dataset for RNASLOpt & Pknots [.zip] - may take several seconds...
Overview
| Metric | RNASLOpt | Pknots | |
|---|---|---|---|
| MCC | 0.591 | > | 0.547 |
| Average MCC ± 95% Confidence Intervals | 0.668 ± 0.115 | > | 0.661 ± 0.120 |
| Sensitivity | 0.498 | > | 0.497 |
| Positive Predictive Value | 0.709 | > | 0.611 |
| Total TP | 302 | > | 301 |
| Total TN | 64164 | > | 64097 |
| Total FP | 141 | < | 216 |
| Total FP CONTRA | 16 | < | 19 |
| Total FP INCONS | 108 | < | 173 |
| Total FP COMP | 17 | < | 24 |
| Total FN | 304 | < | 305 |
| P-value | 4.48494289621e-08 | ||
Performance plots
Performance of RNASLOpt - scored higher in this pairwise comparison
1. Total counts & total scores for RNASLOpt
| Total Base Pair Counts | |
|---|---|
| Total TP | 302 |
| Total TN | 64164 |
| Total FP | 141 |
| Total FP CONTRA | 16 |
| Total FP INCONS | 108 |
| Total FP COMP | 17 |
| Total FN | 304 |
| Total Scores | |
|---|---|
| MCC | 0.591 |
| Average MCC ± 95% Confidence Intervals | 0.668 ± 0.115 |
| Sensitivity | 0.498 |
| Positive Predictive Value | 0.709 |
| Nr of predictions | 30 |
2. Individual counts for RNASLOpt [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2LC8_A | 0.47 | 0.35 | 0.64 | 7 | 1529 | 4 | 0 | 4 | 0 | 13 | |
| 2LDL_A | - | 0.90 | 0.82 | 1.00 | 9 | 342 | 1 | 0 | 0 | 1 | 2 |
| 2LHP_A | - | 0.97 | 0.94 | 1.00 | 15 | 651 | 0 | 0 | 0 | 0 | 1 |
| 2LI4_A | - | 0.93 | 0.88 | 1.00 | 14 | 482 | 0 | 0 | 0 | 0 | 2 |
| 2LJJ_A | - | 1.00 | 1.00 | 1.00 | 8 | 343 | 2 | 0 | 0 | 2 | 0 |
| 2LK3_A | - | 0.95 | 0.90 | 1.00 | 9 | 267 | 0 | 0 | 0 | 0 | 1 |
| 2LKR_A | - | 0.68 | 0.62 | 0.75 | 24 | 6073 | 9 | 0 | 8 | 1 | 15 |
| 2LQZ_A | - | 0.85 | 0.82 | 0.90 | 9 | 341 | 1 | 1 | 0 | 0 | 2 |
| 2LWK_A | - | 0.83 | 0.77 | 0.91 | 10 | 485 | 1 | 0 | 1 | 0 | 3 |
| 3J0L_8 | - | 0.70 | 0.50 | 1.00 | 4 | 186 | 0 | 0 | 0 | 0 | 4 |
| 3J0L_a | - | 0.26 | 0.19 | 0.38 | 3 | 1120 | 5 | 1 | 4 | 0 | 13 |
| 3J0L_1 | - | 0.65 | 0.47 | 0.90 | 9 | 1215 | 3 | 0 | 1 | 2 | 10 |
| 3J0L_h | - | 0.70 | 0.49 | 1.00 | 21 | 6084 | 0 | 0 | 0 | 0 | 22 |
| 3J0L_7 | - | -0.01 | 0.00 | 0.00 | 0 | 1212 | 13 | 0 | 13 | 0 | 17 |
| 3J0L_g | - | -0.01 | 0.00 | 0.00 | 0 | 461 | 4 | 1 | 3 | 0 | 4 |
| 3J0L_2 | - | 0.39 | 0.36 | 0.43 | 12 | 6188 | 18 | 2 | 14 | 2 | 21 |
| 3J16_L | 0.53 | 0.40 | 0.71 | 12 | 2758 | 5 | 0 | 5 | 0 | 18 | |
| 3SN2_B | 0.96 | 0.92 | 1.00 | 11 | 395 | 0 | 0 | 0 | 0 | 1 | |
| 3TRZ_Z | - | 0.91 | 0.83 | 1.00 | 5 | 205 | 2 | 0 | 0 | 2 | 1 |
| 3TS0_U | - | 1.00 | 1.00 | 1.00 | 6 | 247 | 1 | 0 | 0 | 1 | 0 |
| 3TS2_V | - | 1.00 | 1.00 | 1.00 | 5 | 271 | 0 | 0 | 0 | 0 | 0 |
| 3U4M_B | - | 0.38 | 0.32 | 0.46 | 12 | 3134 | 14 | 0 | 14 | 0 | 25 |
| 3UZL_B | 0.48 | 0.32 | 0.71 | 12 | 3553 | 5 | 0 | 5 | 0 | 25 | |
| 3VJR_D | - | 0.96 | 0.92 | 1.00 | 12 | 618 | 0 | 0 | 0 | 0 | 1 |
| 4A1C_3 | 0.67 | 0.52 | 0.88 | 28 | 7108 | 4 | 0 | 4 | 0 | 26 | |
| 4A1C_2 | 0.23 | 0.24 | 0.22 | 8 | 11744 | 35 | 8 | 21 | 6 | 25 | |
| 4A4U_A | - | 1.00 | 1.00 | 1.00 | 9 | 222 | 0 | 0 | 0 | 0 | 0 |
| 4AOB_A | 0.26 | 0.19 | 0.38 | 8 | 4350 | 13 | 2 | 11 | 0 | 34 | |
| 4ENB_A | 0.76 | 0.58 | 1.00 | 11 | 1264 | 0 | 0 | 0 | 0 | 8 | |
| 4ENC_A | 0.65 | 0.47 | 0.90 | 9 | 1316 | 1 | 1 | 0 | 0 | 10 |
Performance of Pknots - scored lower in this pairwise comparison
1. Total counts & total scores for Pknots
| Total Base Pair Counts | |
|---|---|
| Total TP | 301 |
| Total TN | 64097 |
| Total FP | 216 |
| Total FP CONTRA | 19 |
| Total FP INCONS | 173 |
| Total FP COMP | 24 |
| Total FN | 305 |
| Total Scores | |
|---|---|
| MCC | 0.547 |
| Average MCC ± 95% Confidence Intervals | 0.661 ± 0.120 |
| Sensitivity | 0.497 |
| Positive Predictive Value | 0.611 |
| Nr of predictions | 30 |
2. Individual counts for Pknots [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2LC8_A | 0.79 | 0.75 | 0.83 | 15 | 1522 | 3 | 1 | 2 | 0 | 5 | |
| 2LDL_A | - | 0.90 | 0.82 | 1.00 | 9 | 342 | 1 | 0 | 0 | 1 | 2 |
| 2LHP_A | - | 0.97 | 0.94 | 1.00 | 15 | 651 | 0 | 0 | 0 | 0 | 1 |
| 2LI4_A | - | 0.93 | 0.88 | 1.00 | 14 | 482 | 0 | 0 | 0 | 0 | 2 |
| 2LJJ_A | - | 1.00 | 1.00 | 1.00 | 8 | 343 | 2 | 0 | 0 | 2 | 0 |
| 2LK3_A | - | 0.95 | 0.90 | 1.00 | 9 | 267 | 0 | 0 | 0 | 0 | 1 |
| 2LKR_A | - | 0.44 | 0.44 | 0.45 | 17 | 6067 | 22 | 4 | 17 | 1 | 22 |
| 2LQZ_A | - | 0.85 | 0.82 | 0.90 | 9 | 341 | 1 | 1 | 0 | 0 | 2 |
| 2LWK_A | - | 0.33 | 0.23 | 0.50 | 3 | 490 | 3 | 0 | 3 | 0 | 10 |
| 3J0L_8 | - | 0.93 | 0.88 | 1.00 | 7 | 183 | 0 | 0 | 0 | 0 | 1 |
| 3J0L_a | - | 0.35 | 0.31 | 0.42 | 5 | 1116 | 7 | 1 | 6 | 0 | 11 |
| 3J0L_1 | - | 0.65 | 0.47 | 0.90 | 9 | 1215 | 2 | 0 | 1 | 1 | 10 |
| 3J0L_h | - | 0.58 | 0.49 | 0.70 | 21 | 6075 | 11 | 0 | 9 | 2 | 22 |
| 3J0L_7 | - | 0.28 | 0.29 | 0.29 | 5 | 1208 | 12 | 0 | 12 | 0 | 12 |
| 3J0L_g | - | -0.01 | 0.00 | 0.00 | 0 | 460 | 5 | 2 | 3 | 0 | 4 |
| 3J0L_2 | - | 0.36 | 0.36 | 0.36 | 12 | 6183 | 23 | 3 | 18 | 2 | 21 |
| 3J16_L | 0.34 | 0.30 | 0.41 | 9 | 2753 | 13 | 0 | 13 | 0 | 21 | |
| 3SN2_B | 0.96 | 0.92 | 1.00 | 11 | 395 | 0 | 0 | 0 | 0 | 1 | |
| 3TRZ_Z | - | 0.91 | 0.83 | 1.00 | 5 | 205 | 1 | 0 | 0 | 1 | 1 |
| 3TS0_U | - | 1.00 | 1.00 | 1.00 | 6 | 247 | 1 | 0 | 0 | 1 | 0 |
| 3TS2_V | - | 1.00 | 1.00 | 1.00 | 5 | 271 | 0 | 0 | 0 | 0 | 0 |
| 3U4M_B | - | 0.26 | 0.22 | 0.32 | 8 | 3135 | 17 | 0 | 17 | 0 | 29 |
| 3UZL_B | 0.75 | 0.59 | 0.96 | 22 | 3547 | 1 | 0 | 1 | 0 | 15 | |
| 3VJR_D | - | 0.96 | 0.92 | 1.00 | 12 | 618 | 0 | 0 | 0 | 0 | 1 |
| 4A1C_3 | 0.25 | 0.22 | 0.29 | 12 | 7099 | 29 | 1 | 28 | 0 | 42 | |
| 4A1C_2 | 0.24 | 0.24 | 0.25 | 8 | 11749 | 36 | 3 | 21 | 12 | 25 | |
| 4A4U_A | - | 1.00 | 1.00 | 1.00 | 9 | 222 | 0 | 0 | 0 | 0 | 0 |
| 4AOB_A | 0.17 | 0.14 | 0.21 | 6 | 4343 | 23 | 1 | 21 | 1 | 36 | |
| 4ENB_A | 0.83 | 0.79 | 0.88 | 15 | 1258 | 2 | 1 | 1 | 0 | 4 | |
| 4ENC_A | 0.86 | 0.79 | 0.94 | 15 | 1310 | 1 | 1 | 0 | 0 | 4 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.