CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & RDfolder [.zip] - may take several seconds...


Overview

Metric RNASLOpt RDfolder
MCC 0.571 > 0.481
Average MCC ± 95% Confidence Intervals 0.645 ± 0.178 > 0.561 ± 0.209
Sensitivity 0.462 > 0.379
Positive Predictive Value 0.718 > 0.623
Total TP 117 > 96
Total TN 17360 < 17369
Total FP 52 < 60
Total FP CONTRA 5 = 5
Total FP INCONS 41 < 53
Total FP COMP 6 > 2
Total FN 136 < 157
P-value 1.5677163434e-08

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Performance plots


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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 117
Total TN 17360
Total FP 52
Total FP CONTRA 5
Total FP INCONS 41
Total FP COMP 6
Total FN 136
Total Scores
MCC 0.571
Average MCC ± 95% Confidence Intervals 0.645 ± 0.178
Sensitivity 0.462
Positive Predictive Value 0.718
Nr of predictions 17

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_8 - 0.70 0.50 1.00 4 186 0 0 0 0 4
3J0L_a - 0.26 0.19 0.38 3 1120 5 1 4 0 13
3J0L_1 - 0.65 0.47 0.90 9 1215 3 0 1 2 10
3J16_L 0.53 0.40 0.71 12 2758 5 0 5 0 18
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 2 0 0 2 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 96
Total TN 17369
Total FP 60
Total FP CONTRA 5
Total FP INCONS 53
Total FP COMP 2
Total FN 157
Total Scores
MCC 0.481
Average MCC ± 95% Confidence Intervals 0.561 ± 0.209
Sensitivity 0.379
Positive Predictive Value 0.623
Nr of predictions 17

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1526 14 2 12 0 20
2LDL_A - 0.90 0.82 1.00 9 342 0 0 0 0 2
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
3J0L_7 - -0.01 0.00 0.00 0 1220 5 0 5 0 17
3J0L_g - -0.01 0.00 0.00 0 462 3 1 2 0 4
3J0L_8 - 0.86 0.75 1.00 6 184 0 0 0 0 2
3J0L_a - -0.01 0.00 0.00 0 1124 4 1 3 0 16
3J0L_1 - 0.65 0.47 0.90 9 1215 2 0 1 1 10
3J16_L 0.22 0.17 0.31 5 2759 11 0 11 0 25
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 0 0 0 0 1
3TS0_U - 0.91 0.83 1.00 5 248 0 0 0 0 1
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.43 0.32 0.60 6 1265 4 0 4 0 13
4ENC_A 0.43 0.32 0.60 6 1316 4 0 4 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.