CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of RNAsubopt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & RNAsubopt [.zip] - may take several seconds...


Overview

Metric RNASLOpt RNAsubopt
MCC 0.591 > 0.584
Average MCC ± 95% Confidence Intervals 0.668 ± 0.115 > 0.658 ± 0.128
Sensitivity 0.498 < 0.525
Positive Predictive Value 0.709 > 0.658
Total TP 302 < 318
Total TN 64164 > 64107
Total FP 141 < 191
Total FP CONTRA 16 > 15
Total FP INCONS 108 < 150
Total FP COMP 17 < 26
Total FN 304 > 288
P-value 0.000579628272742

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Performance plots


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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 302
Total TN 64164
Total FP 141
Total FP CONTRA 16
Total FP INCONS 108
Total FP COMP 17
Total FN 304
Total Scores
MCC 0.591
Average MCC ± 95% Confidence Intervals 0.668 ± 0.115
Sensitivity 0.498
Positive Predictive Value 0.709
Nr of predictions 30

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 1.00 1.00 1.00 8 343 2 0 0 2 0
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.68 0.62 0.75 24 6073 9 0 8 1 15
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2LWK_A - 0.83 0.77 0.91 10 485 1 0 1 0 3
3J0L_8 - 0.70 0.50 1.00 4 186 0 0 0 0 4
3J0L_a - 0.26 0.19 0.38 3 1120 5 1 4 0 13
3J0L_1 - 0.65 0.47 0.90 9 1215 3 0 1 2 10
3J0L_h - 0.70 0.49 1.00 21 6084 0 0 0 0 22
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_2 - 0.39 0.36 0.43 12 6188 18 2 14 2 21
3J16_L 0.53 0.40 0.71 12 2758 5 0 5 0 18
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 2 0 0 2 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
3UZL_B 0.48 0.32 0.71 12 3553 5 0 5 0 25
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of RNAsubopt - scored lower in this pairwise comparison

1. Total counts & total scores for RNAsubopt

Total Base Pair Counts
Total TP 318
Total TN 64107
Total FP 191
Total FP CONTRA 15
Total FP INCONS 150
Total FP COMP 26
Total FN 288
Total Scores
MCC 0.584
Average MCC ± 95% Confidence Intervals 0.658 ± 0.128
Sensitivity 0.525
Positive Predictive Value 0.658
Nr of predictions 30

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2. Individual counts for RNAsubopt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 1.00 1.00 1.00 8 343 2 0 0 2 0
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.81 0.77 0.86 30 6070 9 0 5 4 9
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2LWK_A - 0.83 0.77 0.91 10 485 1 0 1 0 3
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_a - 0.35 0.31 0.42 5 1116 7 1 6 0 11
3J0L_1 - 0.76 0.63 0.92 12 1212 2 0 1 1 7
3J0L_h - 0.75 0.60 0.93 26 6077 4 0 2 2 17
3J0L_7 - -0.01 0.00 0.00 0 1213 12 0 12 0 17
3J0L_g - -0.01 0.00 0.00 0 460 5 1 4 0 4
3J0L_2 - 0.25 0.24 0.28 8 6187 25 0 21 4 25
3J16_L 0.41 0.37 0.48 11 2752 12 1 11 0 19
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 1 0 0 1 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
3UZL_B 0.48 0.38 0.61 14 3547 9 0 9 0 23
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.70 0.59 0.82 32 7101 7 1 6 0 22
4A1C_2 0.14 0.15 0.13 5 11742 43 5 29 9 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.52 0.43 0.64 18 4343 11 2 8 1 24
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.32 0.26 0.42 5 1314 7 0 7 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.