CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Vsfold4 [.zip] - may take several seconds...


Overview

Metric RNASLOpt Vsfold4
MCC 0.591 > 0.537
Average MCC ± 95% Confidence Intervals 0.668 ± 0.115 > 0.643 ± 0.119
Sensitivity 0.498 > 0.457
Positive Predictive Value 0.709 > 0.640
Total TP 302 > 277
Total TN 64164 > 64157
Total FP 141 < 175
Total FP CONTRA 16 > 15
Total FP INCONS 108 < 141
Total FP COMP 17 < 19
Total FN 304 < 329
P-value 3.56938820447e-08

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Performance plots


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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 302
Total TN 64164
Total FP 141
Total FP CONTRA 16
Total FP INCONS 108
Total FP COMP 17
Total FN 304
Total Scores
MCC 0.591
Average MCC ± 95% Confidence Intervals 0.668 ± 0.115
Sensitivity 0.498
Positive Predictive Value 0.709
Nr of predictions 30

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.35 0.64 7 1529 4 0 4 0 13
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 1.00 1.00 1.00 8 343 2 0 0 2 0
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.68 0.62 0.75 24 6073 9 0 8 1 15
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2LWK_A - 0.83 0.77 0.91 10 485 1 0 1 0 3
3J0L_8 - 0.70 0.50 1.00 4 186 0 0 0 0 4
3J0L_a - 0.26 0.19 0.38 3 1120 5 1 4 0 13
3J0L_1 - 0.65 0.47 0.90 9 1215 3 0 1 2 10
3J0L_h - 0.70 0.49 1.00 21 6084 0 0 0 0 22
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_2 - 0.39 0.36 0.43 12 6188 18 2 14 2 21
3J16_L 0.53 0.40 0.71 12 2758 5 0 5 0 18
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 2 0 0 2 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
3UZL_B 0.48 0.32 0.71 12 3553 5 0 5 0 25
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 277
Total TN 64157
Total FP 175
Total FP CONTRA 15
Total FP INCONS 141
Total FP COMP 19
Total FN 329
Total Scores
MCC 0.537
Average MCC ± 95% Confidence Intervals 0.643 ± 0.119
Sensitivity 0.457
Positive Predictive Value 0.640
Nr of predictions 30

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1527 13 0 13 0 20
2LDL_A - 0.85 0.73 1.00 8 343 1 0 0 1 3
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LJJ_A - 1.00 1.00 1.00 8 343 2 0 0 2 0
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.31 0.28 0.34 11 6073 21 3 18 0 28
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2LWK_A - 0.83 0.77 0.91 10 485 1 0 1 0 3
3J0L_8 - 0.70 0.50 1.00 4 186 0 0 0 0 4
3J0L_a - 0.39 0.31 0.50 5 1118 5 2 3 0 11
3J0L_1 - 0.28 0.21 0.40 4 1215 6 1 5 0 15
3J0L_h - 0.38 0.28 0.52 12 6082 11 0 11 0 31
3J0L_7 - 0.51 0.41 0.64 7 1214 4 0 4 0 10
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_2 - 0.38 0.36 0.41 12 6187 18 3 14 1 21
3J16_L 0.82 0.67 1.00 20 2755 0 0 0 0 10
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 1 0 0 1 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
3UZL_B 0.53 0.41 0.71 15 3549 6 1 5 0 22
3VJR_D - 0.96 0.92 1.00 12 618 0 0 0 0 1
4A1C_3 0.26 0.22 0.32 12 7103 25 2 23 0 42
4A1C_2 0.28 0.24 0.33 8 11757 28 0 16 12 25
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.42 0.33 0.54 14 4345 13 1 11 1 28
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.69 0.47 1.00 9 1317 0 0 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.