CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of ProbKnot - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & ProbKnot [.zip] - may take several seconds...


Overview

Metric RNASampler(20) ProbKnot
MCC 0.625 > 0.586
Average MCC ± 95% Confidence Intervals 0.638 ± 0.100 > 0.605 ± 0.109
Sensitivity 0.460 < 0.529
Positive Predictive Value 0.851 > 0.653
Total TP 348 < 400
Total TN 165508 > 165304
Total FP 97 < 267
Total FP CONTRA 11 < 31
Total FP INCONS 50 < 182
Total FP COMP 36 < 54
Total FN 408 > 356
P-value 2.86595104665e-08

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Performance plots


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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 348
Total TN 165508
Total FP 97
Total FP CONTRA 11
Total FP INCONS 50
Total FP COMP 36
Total FN 408
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.638 ± 0.100
Sensitivity 0.460
Positive Predictive Value 0.851
Nr of predictions 18

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.92 0.90 0.95 18 971 1 0 1 0 2
2XKV_B 0.45 0.20 1.00 4 4556 2 0 0 2 16
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.31 0.10 1.00 4 5147 0 0 0 0 38
3AMU_B 0.82 0.70 0.95 19 2983 3 0 1 2 8
3IZ4_A 0.47 0.32 0.69 42 70815 23 6 13 4 90
3IZF_C 0.74 0.57 0.97 31 6871 1 0 1 0 23
3NPB_A 0.68 0.48 0.96 22 6998 4 1 0 3 24
3O58_3 0.43 0.34 0.55 12 12381 18 2 8 8 23
3O58_2 0.79 0.71 0.87 27 7229 5 2 2 1 11
3PDR_A 0.70 0.53 0.93 38 12839 5 0 3 2 34
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.67 0.48 0.95 20 3895 1 0 1 0 22
4A1C_3 0.74 0.56 1.00 30 7110 0 0 0 0 24
4A1C_2 0.18 0.15 0.23 5 11759 30 0 17 13 28
4AOB_A 0.58 0.40 0.85 17 4351 4 0 3 1 25
4ENB_A 0.60 0.37 1.00 7 1268 0 0 0 0 12
4ENC_A 0.76 0.58 1.00 11 1315 0 0 0 0 8

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Performance of ProbKnot - scored lower in this pairwise comparison

1. Total counts & total scores for ProbKnot

Total Base Pair Counts
Total TP 400
Total TN 165304
Total FP 267
Total FP CONTRA 31
Total FP INCONS 182
Total FP COMP 54
Total FN 356
Total Scores
MCC 0.586
Average MCC ± 95% Confidence Intervals 0.605 ± 0.109
Sensitivity 0.529
Positive Predictive Value 0.653
Nr of predictions 18

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2. Individual counts for ProbKnot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2XKV_B 0.51 0.50 0.53 10 4541 24 0 9 15 10
2XQD_Y 0.90 0.81 1.00 22 2828 1 0 0 1 5
2XXA_G 0.26 0.24 0.29 10 5116 25 1 24 0 32
3AMU_B 0.65 0.59 0.73 16 2981 8 0 6 2 11
3IZ4_A 0.52 0.46 0.60 61 70774 46 6 35 5 71
3IZF_C 0.72 0.61 0.85 33 6864 6 0 6 0 21
3NPB_A 0.72 0.61 0.85 28 6988 8 1 4 3 18
3O58_3 0.31 0.34 0.29 12 12362 41 4 25 12 23
3O58_2 0.76 0.76 0.76 29 7222 10 3 6 1 9
3PDR_A 0.74 0.64 0.85 46 12826 10 1 7 2 26
3RKF_A 0.73 0.59 0.91 20 2189 2 1 1 0 14
3SD1_A 0.55 0.48 0.65 20 3885 11 2 9 0 22
4A1C_3 0.73 0.61 0.87 33 7102 6 1 4 1 21
4A1C_2 0.13 0.15 0.12 5 11738 49 7 31 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.73 0.58 0.92 11 1263 1 1 0 0 8
4ENC_A 0.45 0.42 0.50 8 1310 8 1 7 0 11

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.