CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RNAalifold(20) Carnac(seed)
MCC 0.627 > 0.197
Average MCC ± 95% Confidence Intervals 0.599 ± 0.077 > 0.092 ± 0.132
Sensitivity 0.477 > 0.039
Positive Predictive Value 0.828 < 1.000
Total TP 356 > 29
Total TN 116940 < 117341
Total FP 101 > 0
Total FP CONTRA 11 > 0
Total FP INCONS 63 > 0
Total FP COMP 27 > 0
Total FN 390 < 717
P-value 5.1503931209e-08

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Performance plots


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Performance of RNAalifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 356
Total TN 116940
Total FP 101
Total FP CONTRA 11
Total FP INCONS 63
Total FP COMP 27
Total FN 390
Total Scores
MCC 0.627
Average MCC ± 95% Confidence Intervals 0.599 ± 0.077
Sensitivity 0.477
Positive Predictive Value 0.828
Nr of predictions 21

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.60 0.36 1.00 4 402 0 0 0 0 7
2L94_A 0.53 0.50 0.59 10 973 7 0 7 0 10
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3GX2_A 0.77 0.60 1.00 24 4347 1 0 0 1 16
3IVN_B 0.74 0.58 0.95 18 2327 1 1 0 0 13
3IZF_C 0.71 0.59 0.86 32 6866 5 1 4 0 22
3JYX_4 0.39 0.30 0.50 10 12226 15 0 10 5 23
3JYX_3 0.60 0.52 0.70 14 6308 17 0 6 11 13
3LA5_A 0.75 0.56 1.00 19 2466 0 0 0 0 15
3NPB_A 0.68 0.48 0.96 22 6998 3 1 0 2 24
3O58_3 0.37 0.26 0.53 9 12386 8 2 6 0 26
3O58_2 0.79 0.76 0.83 29 7225 7 3 3 1 9
3PDR_A 0.76 0.61 0.96 44 12834 3 0 2 1 28
3RKF_A 0.68 0.50 0.94 17 2193 1 0 1 0 17
3SD1_A 0.70 0.60 0.83 25 3886 5 1 4 0 17
4A1C_3 0.74 0.57 0.97 31 7108 1 0 1 0 23
4A1C_2 0.17 0.15 0.19 5 11755 23 2 19 2 28
4AOB_A 0.72 0.52 1.00 22 4349 1 0 0 1 20
4ENB_A 0.46 0.21 1.00 4 1271 0 0 0 0 15
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 29
Total TN 117341
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 717
Total Scores
MCC 0.197
Average MCC ± 95% Confidence Intervals 0.092 ± 0.132
Sensitivity 0.039
Positive Predictive Value 1.000
Nr of predictions 21

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2XKV_B 0.00 0.00 0.00 0 4560 0 0 0 0 20
2XXA_G 0.00 0.00 0.00 0 5151 0 0 0 0 42
3GX2_A 0.00 0.00 0.00 0 4371 0 0 0 0 40
3IVN_B 0.00 0.00 0.00 0 2346 0 0 0 0 31
3IZF_C 0.00 0.00 0.00 0 6903 0 0 0 0 54
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3JYX_3 0.00 0.00 0.00 0 6328 0 0 0 0 27
3LA5_A 0.00 0.00 0.00 0 2485 0 0 0 0 34
3NPB_A 0.00 0.00 0.00 0 7021 0 0 0 0 46
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3O58_2 0.00 0.00 0.00 0 7260 0 0 0 0 38
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.