CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(20) - scored higher in this pairwise comparison

  4. Performance of Fold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(20) & Fold [.zip] - may take several seconds...


Overview

Metric RNAalifold(20) Fold
MCC 0.626 > 0.610
Average MCC ± 95% Confidence Intervals 0.612 ± 0.094 > 0.607 ± 0.115
Sensitivity 0.468 < 0.542
Positive Predictive Value 0.841 > 0.689
Total TP 354 < 410
Total TN 165496 > 165322
Total FP 83 < 237
Total FP CONTRA 14 < 24
Total FP INCONS 53 < 161
Total FP COMP 16 < 52
Total FN 402 > 346
P-value 2.26346675981e-08

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Performance plots


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Performance of RNAalifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 354
Total TN 165496
Total FP 83
Total FP CONTRA 14
Total FP INCONS 53
Total FP COMP 16
Total FN 402
Total Scores
MCC 0.626
Average MCC ± 95% Confidence Intervals 0.612 ± 0.094
Sensitivity 0.468
Positive Predictive Value 0.841
Nr of predictions 18

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.53 0.50 0.59 10 973 7 0 7 0 10
2XKV_B 0.45 0.20 1.00 4 4556 3 0 0 3 16
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.41 0.17 1.00 7 5144 0 0 0 0 35
3AMU_B 0.86 0.74 1.00 20 2983 1 0 0 1 7
3IZ4_A 0.53 0.35 0.82 46 70820 15 4 6 5 86
3IZF_C 0.71 0.59 0.86 32 6866 5 1 4 0 22
3NPB_A 0.68 0.48 0.96 22 6998 3 1 0 2 24
3O58_3 0.37 0.26 0.53 9 12386 8 2 6 0 26
3O58_2 0.79 0.76 0.83 29 7225 7 3 3 1 9
3PDR_A 0.76 0.61 0.96 44 12834 3 0 2 1 28
3RKF_A 0.68 0.50 0.94 17 2193 1 0 1 0 17
3SD1_A 0.70 0.60 0.83 25 3886 5 1 4 0 17
4A1C_3 0.74 0.57 0.97 31 7108 1 0 1 0 23
4A1C_2 0.17 0.15 0.19 5 11755 23 2 19 2 28
4AOB_A 0.72 0.52 1.00 22 4349 1 0 0 1 20
4ENB_A 0.46 0.21 1.00 4 1271 0 0 0 0 15
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of Fold - scored lower in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP 410
Total TN 165322
Total FP 237
Total FP CONTRA 24
Total FP INCONS 161
Total FP COMP 52
Total FN 346
Total Scores
MCC 0.610
Average MCC ± 95% Confidence Intervals 0.607 ± 0.115
Sensitivity 0.542
Positive Predictive Value 0.689
Nr of predictions 18

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2. Individual counts for Fold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2XKV_B 0.51 0.50 0.53 10 4541 24 0 9 15 10
2XQD_Y 0.88 0.78 1.00 21 2829 0 0 0 0 6
2XXA_G 0.93 0.86 1.00 36 5115 0 0 0 0 6
3AMU_B 0.64 0.59 0.70 16 2980 9 0 7 2 11
3IZ4_A 0.53 0.46 0.61 61 70776 44 5 34 5 71
3IZF_C 0.70 0.59 0.82 32 6864 7 1 6 0 22
3NPB_A 0.70 0.61 0.80 28 6986 10 1 6 3 18
3O58_3 0.29 0.31 0.28 11 12363 41 3 26 12 24
3O58_2 0.71 0.71 0.71 27 7222 12 3 8 1 11
3PDR_A 0.77 0.64 0.94 46 12831 5 0 3 2 26
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_3 0.68 0.57 0.82 31 7102 7 1 6 0 23
4A1C_2 0.14 0.15 0.14 5 11744 43 5 27 11 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.32 0.26 0.42 5 1263 7 1 6 0 14
4ENC_A 0.31 0.26 0.38 5 1313 8 1 7 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.