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Table of contents:
- Overview
- Performance Plots
- Performance of RNAalifold(seed) - scored higher in this pairwise comparison
- Performance of RDfolder - scored lower in this pairwise comparison
- Compile and download dataset for RNAalifold(seed) & RDfolder [.zip] - may take several seconds...
Overview
| Metric | RNAalifold(seed) | RDfolder | |
|---|---|---|---|
| MCC | 0.668 | > | 0.603 |
| Average MCC ± 95% Confidence Intervals | 0.636 ± 0.116 | > | 0.617 ± 0.153 |
| Sensitivity | 0.509 | > | 0.493 |
| Positive Predictive Value | 0.884 | > | 0.747 |
| Total TP | 275 | > | 266 |
| Total TN | 43867 | > | 43822 |
| Total FP | 42 | < | 94 |
| Total FP CONTRA | 5 | < | 11 |
| Total FP INCONS | 31 | < | 79 |
| Total FP COMP | 6 | > | 4 |
| Total FN | 265 | < | 274 |
| P-value | 5.10776592382e-08 | ||
Performance plots
Performance of RNAalifold(seed) - scored higher in this pairwise comparison
1. Total counts & total scores for RNAalifold(seed)
| Total Base Pair Counts | |
|---|---|
| Total TP | 275 |
| Total TN | 43867 |
| Total FP | 42 |
| Total FP CONTRA | 5 |
| Total FP INCONS | 31 |
| Total FP COMP | 6 |
| Total FN | 265 |
| Total Scores | |
|---|---|
| MCC | 0.668 |
| Average MCC ± 95% Confidence Intervals | 0.636 ± 0.116 |
| Sensitivity | 0.509 |
| Positive Predictive Value | 0.884 |
| Nr of predictions | 21 |
2. Individual counts for RNAalifold(seed) [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.52 | 0.27 | 1.00 | 3 | 403 | 0 | 0 | 0 | 0 | 8 | |
| 2KE6_A | 0.97 | 0.95 | 1.00 | 18 | 1110 | 1 | 0 | 0 | 1 | 1 | |
| 2KUR_A | 0.95 | 0.90 | 1.00 | 19 | 1109 | 0 | 0 | 0 | 0 | 2 | |
| 2KUU_A | 0.92 | 0.86 | 1.00 | 18 | 1110 | 1 | 0 | 0 | 1 | 3 | |
| 2KUV_A | 0.93 | 0.86 | 1.00 | 19 | 1109 | 0 | 0 | 0 | 0 | 3 | |
| 2KUW_A | 0.84 | 0.76 | 0.94 | 16 | 1111 | 1 | 0 | 1 | 0 | 5 | |
| 2KX8_A | 0.00 | 0.00 | 0.00 | 0 | 861 | 0 | 0 | 0 | 0 | 18 | |
| 2L1F_A | 0.67 | 0.58 | 0.78 | 14 | 2062 | 4 | 0 | 4 | 0 | 10 | |
| 2L1F_B | 0.64 | 0.56 | 0.74 | 14 | 2126 | 5 | 0 | 5 | 0 | 11 | |
| 2L94_A | 0.59 | 0.40 | 0.89 | 8 | 981 | 1 | 0 | 1 | 0 | 12 | |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1528 | 12 | 0 | 12 | 0 | 20 | |
| 2XKV_B | 0.59 | 0.35 | 1.00 | 7 | 4553 | 2 | 0 | 0 | 2 | 13 | |
| 3A3A_A | 0.71 | 0.51 | 1.00 | 19 | 3636 | 0 | 0 | 0 | 0 | 18 | |
| 3GX2_A | 0.74 | 0.55 | 1.00 | 22 | 4349 | 1 | 0 | 0 | 1 | 18 | |
| 3IVN_B | 0.61 | 0.48 | 0.79 | 15 | 2327 | 4 | 2 | 2 | 0 | 16 | |
| 3LA5_A | 0.63 | 0.47 | 0.84 | 16 | 2466 | 3 | 1 | 2 | 0 | 18 | |
| 3RKF_A | 0.63 | 0.47 | 0.84 | 16 | 2192 | 3 | 1 | 2 | 0 | 18 | |
| 3SD1_A | 0.58 | 0.40 | 0.85 | 17 | 3896 | 3 | 1 | 2 | 0 | 25 | |
| 4AOB_A | 0.72 | 0.52 | 1.00 | 22 | 4349 | 1 | 0 | 0 | 1 | 20 | |
| 4ENB_A | 0.56 | 0.32 | 1.00 | 6 | 1269 | 0 | 0 | 0 | 0 | 13 | |
| 4ENC_A | 0.56 | 0.32 | 1.00 | 6 | 1320 | 0 | 0 | 0 | 0 | 13 |
Performance of RDfolder - scored lower in this pairwise comparison
1. Total counts & total scores for RDfolder
| Total Base Pair Counts | |
|---|---|
| Total TP | 266 |
| Total TN | 43822 |
| Total FP | 94 |
| Total FP CONTRA | 11 |
| Total FP INCONS | 79 |
| Total FP COMP | 4 |
| Total FN | 274 |
| Total Scores | |
|---|---|
| MCC | 0.603 |
| Average MCC ± 95% Confidence Intervals | 0.617 ± 0.153 |
| Sensitivity | 0.493 |
| Positive Predictive Value | 0.747 |
| Nr of predictions | 21 |
2. Individual counts for RDfolder [ download as .csv ]
| RNA Chain | Rfam family | MCC | SENS | PPV | TP | TN | FP | FP CONTRA | FP INCONS | FP COMP | FN |
| 2KDQ_B | 0.95 | 0.91 | 1.00 | 10 | 396 | 0 | 0 | 0 | 0 | 1 | |
| 2KE6_A | 0.89 | 0.79 | 1.00 | 15 | 1113 | 1 | 0 | 0 | 1 | 4 | |
| 2KUR_A | 0.87 | 0.76 | 1.00 | 16 | 1112 | 0 | 0 | 0 | 0 | 5 | |
| 2KUU_A | 0.84 | 0.71 | 1.00 | 15 | 1113 | 1 | 0 | 0 | 1 | 6 | |
| 2KUV_A | 0.85 | 0.73 | 1.00 | 16 | 1112 | 0 | 0 | 0 | 0 | 6 | |
| 2KUW_A | 0.87 | 0.76 | 1.00 | 16 | 1112 | 0 | 0 | 0 | 0 | 5 | |
| 2KX8_A | 0.88 | 0.78 | 1.00 | 14 | 847 | 0 | 0 | 0 | 0 | 4 | |
| 2L1F_A | -0.01 | 0.00 | 0.00 | 0 | 2067 | 13 | 2 | 11 | 0 | 24 | |
| 2L1F_B | 0.98 | 0.96 | 1.00 | 24 | 2121 | 0 | 0 | 0 | 0 | 1 | |
| 2L94_A | 0.97 | 0.95 | 1.00 | 19 | 971 | 0 | 0 | 0 | 0 | 1 | |
| 2LC8_A | -0.01 | 0.00 | 0.00 | 0 | 1526 | 14 | 2 | 12 | 0 | 20 | |
| 2XKV_B | 0.00 | 0.00 | 0.00 | 0 | 4538 | 22 | 5 | 17 | 0 | 20 | |
| 3A3A_A | 0.53 | 0.41 | 0.71 | 15 | 3634 | 6 | 0 | 6 | 0 | 22 | |
| 3GX2_A | 0.50 | 0.40 | 0.64 | 16 | 4346 | 10 | 1 | 8 | 1 | 24 | |
| 3IVN_B | 0.78 | 0.61 | 1.00 | 19 | 2327 | 0 | 0 | 0 | 0 | 12 | |
| 3LA5_A | 0.78 | 0.62 | 1.00 | 21 | 2464 | 0 | 0 | 0 | 0 | 13 | |
| 3RKF_A | 0.76 | 0.59 | 1.00 | 20 | 2191 | 0 | 0 | 0 | 0 | 14 | |
| 3SD1_A | 0.30 | 0.17 | 0.54 | 7 | 3903 | 6 | 0 | 6 | 0 | 35 | |
| 4AOB_A | 0.35 | 0.26 | 0.48 | 11 | 4348 | 13 | 1 | 11 | 1 | 31 | |
| 4ENB_A | 0.43 | 0.32 | 0.60 | 6 | 1265 | 4 | 0 | 4 | 0 | 13 | |
| 4ENC_A | 0.43 | 0.32 | 0.60 | 6 | 1316 | 4 | 0 | 4 | 0 | 13 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.