CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAfold - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAfold & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNAfold CRWrnafold
MCC 0.610 > 0.585
Average MCC ± 95% Confidence Intervals 0.651 ± 0.122 > 0.639 ± 0.123
Sensitivity 0.545 > 0.522
Positive Predictive Value 0.691 > 0.663
Total TP 358 > 343
Total TN 69823 < 69824
Total FP 188 < 196
Total FP CONTRA 20 < 24
Total FP INCONS 140 < 150
Total FP COMP 28 > 22
Total FN 299 < 314
P-value 5.6410608252e-08

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Performance plots


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Performance of RNAfold - scored higher in this pairwise comparison

1. Total counts & total scores for RNAfold

Total Base Pair Counts
Total TP 358
Total TN 69823
Total FP 188
Total FP CONTRA 20
Total FP INCONS 140
Total FP COMP 28
Total FN 299
Total Scores
MCC 0.610
Average MCC ± 95% Confidence Intervals 0.651 ± 0.122
Sensitivity 0.545
Positive Predictive Value 0.691
Nr of predictions 32

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2. Individual counts for RNAfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LBS_A - 1.00 1.00 1.00 14 482 0 0 0 0 0
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
2LDL_A - 0.90 0.82 1.00 9 342 1 0 0 1 2
2LDT_A - 0.85 0.73 1.00 11 454 0 0 0 0 4
2LHP_A - 0.97 0.94 1.00 15 651 0 0 0 0 1
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.93 0.87 1.00 34 6071 3 0 0 3 5
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2YIE_Z - -0.01 0.00 0.00 0 1525 15 3 12 0 12
2YIE_X - 0.25 0.25 0.27 3 1367 11 1 7 3 9
3AMU_B 0.70 0.59 0.84 16 2984 5 0 3 2 11
3J0L_7 - -0.01 0.00 0.00 0 1213 12 0 12 0 17
3J0L_g - -0.01 0.00 0.00 0 460 5 1 4 0 4
3J0L_2 - 0.25 0.24 0.26 8 6185 25 2 21 2 25
3J0L_h - 0.75 0.60 0.93 26 6077 4 0 2 2 17
3J0L_a - 0.23 0.19 0.30 3 1118 7 1 6 0 13
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_1 - 0.76 0.63 0.92 12 1212 2 0 1 1 7
3J16_L 0.75 0.57 1.00 17 2758 0 0 0 0 13
3SD1_A 0.64 0.52 0.79 22 3888 6 1 5 0 20
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 1 0 0 1 1
3TS0_U - 1.00 1.00 1.00 6 247 1 0 0 1 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
4A1C_3 0.70 0.59 0.82 32 7101 7 1 6 0 22
4A1C_2 0.14 0.15 0.14 5 11744 43 5 27 11 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.32 0.26 0.42 5 1314 7 1 6 0 14

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 343
Total TN 69824
Total FP 196
Total FP CONTRA 24
Total FP INCONS 150
Total FP COMP 22
Total FN 314
Total Scores
MCC 0.585
Average MCC ± 95% Confidence Intervals 0.639 ± 0.123
Sensitivity 0.522
Positive Predictive Value 0.663
Nr of predictions 32

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LBS_A - 1.00 1.00 1.00 14 482 0 0 0 0 0
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
2LDL_A - 0.85 0.73 1.00 8 343 1 0 0 1 3
2LDT_A - 0.85 0.73 1.00 11 454 0 0 0 0 4
2LHP_A - 0.93 0.88 1.00 14 652 0 0 0 0 2
2LI4_A - 0.93 0.88 1.00 14 482 0 0 0 0 2
2LK3_A - 0.95 0.90 1.00 9 267 0 0 0 0 1
2LKR_A - 0.52 0.44 0.63 17 6078 12 2 8 2 22
2LQZ_A - 0.85 0.82 0.90 9 341 1 1 0 0 2
2YIE_Z - -0.01 0.00 0.00 0 1525 15 3 12 0 12
2YIE_X - 0.36 0.33 0.40 4 1368 9 2 4 3 8
3AMU_B 0.67 0.59 0.76 16 2982 7 0 5 2 11
3J0L_7 - -0.01 0.00 0.00 0 1212 13 0 13 0 17
3J0L_g - -0.01 0.00 0.00 0 461 4 1 3 0 4
3J0L_2 - 0.25 0.24 0.28 8 6187 23 2 19 2 25
3J0L_h - 0.81 0.65 1.00 28 6077 0 0 0 0 15
3J0L_a - 0.39 0.31 0.50 5 1118 5 1 4 0 11
3J0L_8 - 0.93 0.88 1.00 7 183 0 0 0 0 1
3J0L_1 - 0.76 0.63 0.92 12 1212 3 0 1 2 7
3J16_L 0.84 0.70 1.00 21 2754 0 0 0 0 9
3SD1_A 0.52 0.45 0.61 19 3885 12 2 10 0 23
3SN2_B 0.96 0.92 1.00 11 395 0 0 0 0 1
3TRZ_Z - 0.91 0.83 1.00 5 205 0 0 0 0 1
3TS0_U - 1.00 1.00 1.00 6 247 0 0 0 0 0
3TS2_V - 1.00 1.00 1.00 5 271 0 0 0 0 0
3U4M_B - 0.38 0.32 0.46 12 3134 14 0 14 0 25
4A1C_3 0.70 0.59 0.84 32 7102 6 0 6 0 22
4A1C_2 0.13 0.15 0.13 5 11741 44 4 31 9 28
4A4U_A - 1.00 1.00 1.00 9 222 0 0 0 0 0
4AOB_A 0.59 0.48 0.74 20 4344 8 2 5 1 22
4ENB_A 0.70 0.58 0.85 11 1262 2 1 1 0 8
4ENC_A 0.70 0.58 0.85 11 1313 2 1 1 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.