CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAshapes - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAshapes & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric RNAshapes RNASampler(seed)
MCC 0.696 > 0.673
Average MCC ± 95% Confidence Intervals 0.754 ± 0.135 > 0.690 ± 0.136
Sensitivity 0.641 > 0.535
Positive Predictive Value 0.760 < 0.851
Total TP 288 > 240
Total TN 60980 < 61077
Total FP 131 > 59
Total FP CONTRA 13 > 4
Total FP INCONS 78 > 38
Total FP COMP 40 > 17
Total FN 161 < 209
P-value 1.21817282663e-08

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Performance plots


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Performance of RNAshapes - scored higher in this pairwise comparison

1. Total counts & total scores for RNAshapes

Total Base Pair Counts
Total TP 288
Total TN 60980
Total FP 131
Total FP CONTRA 13
Total FP INCONS 78
Total FP COMP 40
Total FN 161
Total Scores
MCC 0.696
Average MCC ± 95% Confidence Intervals 0.754 ± 0.135
Sensitivity 0.641
Positive Predictive Value 0.760
Nr of predictions 17

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2. Individual counts for RNAshapes [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.97 0.95 1.00 18 1110 1 0 0 1 1
2KUR_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2KUU_A 0.92 0.86 1.00 18 1110 1 0 0 1 3
2KUV_A 0.93 0.86 1.00 19 1109 0 0 0 0 3
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_A 0.87 0.83 0.91 20 2058 2 0 2 0 4
2L1F_B 0.96 0.92 1.00 23 2122 0 0 0 0 2
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
3A3A_A 0.76 0.65 0.89 24 3628 3 0 3 0 13
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.31 0.30 0.31 10 12214 35 5 17 13 23
3O58_3 0.34 0.34 0.34 12 12368 37 2 21 14 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.64 0.52 0.79 22 3888 6 1 5 0 20
4A1C_2 0.14 0.15 0.14 5 11746 41 5 25 11 28

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 240
Total TN 61077
Total FP 59
Total FP CONTRA 4
Total FP INCONS 38
Total FP COMP 17
Total FN 209
Total Scores
MCC 0.673
Average MCC ± 95% Confidence Intervals 0.690 ± 0.136
Sensitivity 0.535
Positive Predictive Value 0.851
Nr of predictions 17

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.92 0.84 1.00 16 1112 1 0 0 1 3
2KUR_A 0.90 0.81 1.00 17 1111 0 0 0 0 4
2KUU_A 0.87 0.76 1.00 16 1112 1 0 0 1 5
2KUV_A 0.88 0.77 1.00 17 1111 0 0 0 0 5
2KUW_A 0.90 0.81 1.00 17 1111 0 0 0 0 4
2L1F_A 0.81 0.67 1.00 16 2064 0 0 0 0 8
2L1F_B 0.82 0.68 1.00 17 2128 0 0 0 0 8
2L94_A 0.71 0.55 0.92 11 978 1 0 1 0 9
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3A3A_A 0.70 0.49 1.00 18 3637 0 0 0 0 19
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.39 0.30 0.50 10 12226 13 2 8 3 23
3O58_3 0.45 0.34 0.60 12 12383 12 2 6 4 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.