CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of UNAFold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for UNAFold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric UNAFold RNASampler(seed)
MCC 0.690 > 0.673
Average MCC ± 95% Confidence Intervals 0.733 ± 0.168 > 0.690 ± 0.136
Sensitivity 0.635 > 0.535
Positive Predictive Value 0.754 < 0.851
Total TP 285 > 240
Total TN 60981 < 61077
Total FP 129 > 59
Total FP CONTRA 12 > 4
Total FP INCONS 81 > 38
Total FP COMP 36 > 17
Total FN 164 < 209
P-value 1.64481516727e-08

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Performance plots


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Performance of UNAFold - scored higher in this pairwise comparison

1. Total counts & total scores for UNAFold

Total Base Pair Counts
Total TP 285
Total TN 60981
Total FP 129
Total FP CONTRA 12
Total FP INCONS 81
Total FP COMP 36
Total FN 164
Total Scores
MCC 0.690
Average MCC ± 95% Confidence Intervals 0.733 ± 0.168
Sensitivity 0.635
Positive Predictive Value 0.754
Nr of predictions 17

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2. Individual counts for UNAFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.97 0.95 1.00 18 1110 1 0 0 1 1
2KUR_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2KUU_A 0.92 0.86 1.00 18 1110 1 0 0 1 3
2KUV_A 0.93 0.86 1.00 19 1109 0 0 0 0 3
2KUW_A 0.95 0.90 1.00 19 1109 0 0 0 0 2
2L1F_A 0.98 0.96 1.00 23 2057 0 0 0 0 1
2L1F_B 0.98 0.96 1.00 24 2121 0 0 0 0 1
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
3A3A_A 0.87 0.76 1.00 28 3627 0 0 0 0 9
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.32 0.30 0.34 10 12217 31 3 16 12 23
3O58_3 0.35 0.34 0.35 12 12369 33 1 21 11 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.64 0.52 0.79 22 3888 6 1 5 0 20
4A1C_2 0.14 0.15 0.14 5 11745 42 5 26 11 28

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 240
Total TN 61077
Total FP 59
Total FP CONTRA 4
Total FP INCONS 38
Total FP COMP 17
Total FN 209
Total Scores
MCC 0.673
Average MCC ± 95% Confidence Intervals 0.690 ± 0.136
Sensitivity 0.535
Positive Predictive Value 0.851
Nr of predictions 17

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2KE6_A 0.92 0.84 1.00 16 1112 1 0 0 1 3
2KUR_A 0.90 0.81 1.00 17 1111 0 0 0 0 4
2KUU_A 0.87 0.76 1.00 16 1112 1 0 0 1 5
2KUV_A 0.88 0.77 1.00 17 1111 0 0 0 0 5
2KUW_A 0.90 0.81 1.00 17 1111 0 0 0 0 4
2L1F_A 0.81 0.67 1.00 16 2064 0 0 0 0 8
2L1F_B 0.82 0.68 1.00 17 2128 0 0 0 0 8
2L94_A 0.71 0.55 0.92 11 978 1 0 1 0 9
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
3A3A_A 0.70 0.49 1.00 18 3637 0 0 0 0 19
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3JYX_4 0.39 0.30 0.50 10 12226 13 2 8 3 23
3O58_3 0.45 0.34 0.60 12 12383 12 2 6 4 23
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.