CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Alterna - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Alterna & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric Alterna RNASampler(seed)
MCC 0.732 > 0.710
Average MCC ± 95% Confidence Intervals 0.718 ± 0.243 > 0.656 ± 0.484
Sensitivity 0.702 > 0.589
Positive Predictive Value 0.777 < 0.869
Total TP 87 > 73
Total TN 5218 < 5246
Total FP 25 > 11
Total FP CONTRA 7 > 0
Total FP INCONS 18 > 11
Total FP COMP 0 = 0
Total FN 37 < 51
P-value 0.0

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Performance plots


  1. Comparison of performance of Alterna and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Alterna and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Alterna and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Alterna and RNASampler(seed)).

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Performance of Alterna - scored higher in this pairwise comparison

1. Total counts & total scores for Alterna

Total Base Pair Counts
Total TP 87
Total TN 5218
Total FP 25
Total FP CONTRA 7
Total FP INCONS 18
Total FP COMP 0
Total FN 37
Total Scores
MCC 0.732
Average MCC ± 95% Confidence Intervals 0.718 ± 0.243
Sensitivity 0.702
Positive Predictive Value 0.777
Nr of predictions 5

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2. Individual counts for Alterna [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.44 0.53 8 513 7 0 7 0 10
3A3A_A 0.93 0.87 1.00 26 1474 0 0 0 0 4
3IVN_B 0.81 0.78 0.86 18 882 3 2 1 0 5
3RKF_A 0.82 0.79 0.86 19 844 3 1 2 0 5
3SD1_A 0.55 0.55 0.57 16 1505 12 4 8 0 13

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 73
Total TN 5246
Total FP 11
Total FP CONTRA 0
Total FP INCONS 11
Total FP COMP 0
Total FN 51
Total Scores
MCC 0.710
Average MCC ± 95% Confidence Intervals 0.656 ± 0.484
Sensitivity 0.589
Positive Predictive Value 0.869
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3A3A_A 0.77 0.60 1.00 18 1482 0 0 0 0 12
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.