CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & NanoFolder [.zip] - may take several seconds...


Overview

Metric CRWrnafold NanoFolder
MCC 0.437 > 0.427
Average MCC ± 95% Confidence Intervals 0.443 ± 0.452 < 0.470 ± 0.376
Sensitivity 0.462 < 0.519
Positive Predictive Value 0.429 > 0.365
Total TP 48 < 54
Total TN 8141 > 8105
Total FP 83 < 113
Total FP CONTRA 18 < 31
Total FP INCONS 46 < 63
Total FP COMP 19 = 19
Total FN 56 > 50
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CRWrnafold and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and NanoFolder).

^top





Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 48
Total TN 8141
Total FP 83
Total FP CONTRA 18
Total FP INCONS 46
Total FP COMP 19
Total FN 56
Total Scores
MCC 0.437
Average MCC ± 95% Confidence Intervals 0.443 ± 0.452
Sensitivity 0.462
Positive Predictive Value 0.429
Nr of predictions 5

^top



2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3U4M_B - 0.49 0.55 0.46 12 1250 14 3 11 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

^top



Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 54
Total TN 8105
Total FP 113
Total FP CONTRA 31
Total FP INCONS 63
Total FP COMP 19
Total FN 50
Total Scores
MCC 0.427
Average MCC ± 95% Confidence Intervals 0.470 ± 0.376
Sensitivity 0.519
Positive Predictive Value 0.365
Nr of predictions 5

^top



2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3U4M_B - 0.77 0.91 0.67 20 1246 12 6 4 2 2
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.