CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & RDfolder [.zip] - may take several seconds...


Overview

Metric CRWrnafold RDfolder
MCC 0.580 > 0.310
Average MCC ± 95% Confidence Intervals 0.566 ± 0.356 > 0.279 ± 0.251
Sensitivity 0.556 > 0.256
Positive Predictive Value 0.625 > 0.405
Total TP 65 > 30
Total TN 4773 < 4803
Total FP 45 = 45
Total FP CONTRA 16 > 10
Total FP INCONS 23 < 34
Total FP COMP 6 > 1
Total FN 52 < 87
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CRWrnafold and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and RDfolder).

^top





Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 65
Total TN 4773
Total FP 45
Total FP CONTRA 16
Total FP INCONS 23
Total FP COMP 6
Total FN 52
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.566 ± 0.356
Sensitivity 0.556
Positive Predictive Value 0.625
Nr of predictions 6

^top



2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3J0L_a - 0.39 0.36 0.44 4 402 6 3 2 1 7
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

^top



Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 30
Total TN 4803
Total FP 45
Total FP CONTRA 10
Total FP INCONS 34
Total FP COMP 1
Total FN 87
Total Scores
MCC 0.310
Average MCC ± 95% Confidence Intervals 0.279 ± 0.251
Sensitivity 0.256
Positive Predictive Value 0.405
Nr of predictions 6

^top



2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 514 14 3 11 0 18
3J0L_a - -0.02 0.00 0.00 0 407 4 3 1 0 11
3SD1_A 0.35 0.24 0.54 7 1520 6 1 5 0 22
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 0.48 0.40 0.60 6 462 4 0 4 0 9
4ENC_A 0.48 0.40 0.60 6 486 4 0 4 0 9

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.